CAJ | 학술논문

目的：探讨OSAHS患者夜间低氧血症与血压波动之间的关系。方法：选取经PSG确诊为OSAHS的成年患者，同期行夜间动态血压监测检查，分析和比较各PSG指标与OSAHS患者高血压合并症及患者夜间血压波动的关系。结果：63例入选病例中，高血压合并症患病率42.9%；BMI与氧减饱和度事件累积时间占总睡眠时间的百分比(DT)是OSAHS患者高血压合并症患病率的独立影响因素(P<0.05)。DT与NREM%是OSAHS患者夜间舒张压差增大的危险因素(均P<0.05)。BMI是夜间血压基础水平的独立危险因素(P<0.05)。结论：肥胖、夜间低氧事件持续时间长及睡眠结构中NREM期睡眠占比较多的OSAHS患者需警惕高血压合并症的发生发展。
목적：탐토OSAHS환자야간저양혈증여혈압파동지간적관계。방법：선취경PSG학진위OSAHS적성년환자，동기행야간동태혈압감측검사，분석화비교각PSG지표여OSAHS환자고혈압합병증급환자야간혈압파동적관계。결과：63례입선병례중，고혈압합병증환병솔42.9%；BMI여양감포화도사건루적시간점총수면시간적백분비(DT)시OSAHS환자고혈압합병증환병솔적독립영향인소(P<0.05)。DT여NREM%시OSAHS환자야간서장압차증대적위험인소(균P<0.05)。BMI시야간혈압기출수평적독립위험인소(P<0.05)。결론：비반、야간저양사건지속시간장급수면결구중NREM기수면점비교다적OSAHS환자수경척고혈압합병증적발생발전。
Objective:To explore the relationship between polysomnography(PSG) findings and nocturnal blood pressure,and find out a predictable index for hypertension comorbidity associated with obstructive sleep apnea hypopnea syndrome(OSAHS).Method:63 patents with a diagnosis of OSAHS did the PSG concurrently with nocturnal ambulatory blood pressure monitor in lab.Regression analysis was applied to evaluate the relationship between PSG data and nocturnal blood pressure data.Result:The morbidity of hypertension in OSAHS patients was 42.9%.BMI was an independent influencing factor of the nocturnal basal blood pressure level(P<0.05).DT and NREM% were the risk factors of nocturnal variation in diastolic pressure(P<0.05).Conclusion:BMI mainly determines the baseline of nocturnal blood pressure,while nocturnal duration of hypoxemia and sleep structure disturbance mainly affect the nocturnal diastolic pressure fluctuation.OSA patients with obesity,higher DT or NREM% in the PSG should be alerted to the potential of having hypertension comorbidity.