CAJ | 학술논문

目的：了解血培养中常见病原菌的组成以及各类病原菌对抗菌药物的耐药性，为临床医生合理选用抗菌药物解决患者病痛提供依据。方法收集临床送检的血培养标本，应用法国生物梅里埃公司 BacT／Alert3D 全自动血培养仪、配套培养基、鉴定仪系统鉴定菌种及药敏试验。结果1764份血培养分离出病原菌179株，其阳性率为10．1％，其中革兰阳性菌68株（38．0％），革兰阴性菌111株（62．0％）；病原菌中占首位的是大肠埃希菌，其次是凝固酶阴性菌、肺炎克雷伯菌、铜绿假单胞菌。药敏结果显示绝大部分检出的病原菌均有耐药情况出现。结论临床医生应重视患者早期的血培养检验，并严格根据药敏结果合理使用抗菌药物。对血培养的检测应更加规范，从而提高病原菌的检出率，并及时检测病原菌变化及耐药趋势。
목적：료해혈배양중상견병원균적조성이급각류병원균대항균약물적내약성，위림상의생합리선용항균약물해결환자병통제공의거。방법수집림상송검적혈배양표본，응용법국생물매리애공사 BacT／Alert3D 전자동혈배양의、배투배양기、감정의계통감정균충급약민시험。결과1764빈혈배양분리출병원균179주，기양성솔위10．1％，기중혁란양성균68주（38．0％），혁란음성균111주（62．0％）；병원균중점수위적시대장애희균，기차시응고매음성균、폐염극뢰백균、동록가단포균。약민결과현시절대부분검출적병원균균유내약정황출현。결론림상의생응중시환자조기적혈배양검험，병엄격근거약민결과합리사용항균약물。대혈배양적검측응경가규범，종이제고병원균적검출솔，병급시검측병원균변화급내약추세。
Objective To understand the composition of the common pathogens in blood culture and a variety of pathogens to antimicrobial agents in the hospital.To offer the basis for the rational use of antimicrobial drugs to solve the patients'pain.Methods The collection involved 1 764 blood samples.France bioMérieux BacT/Alert3D fully automatic blood culture instrument, supporting medium,identification system were used to identify the pathogens and susceptibility test.Results A total of 1 764 blood samples showed the culture positive rate 10.1%,and there were 179 isolated positive bacteria,among which gram-positive bacteria were 68 (38.0%),gram-negative bacteria 111 (62.0%),at the first place of pathogens as E.coli followed by coagulase-negative bacteria,Klebsiella pneumonia,Pseudomonas aeruginosa.The susceptibility results showed that most of the detected pathogens were resistant to different anti-bacteria agents. Conclusion Clinicians should pay attention to early blood culture of patients,and strictly stick to the rational use of antimicrobial agents based on susceptibility results.