CAJ | 학술논문

目的：观察颈部彩色超声在食管上段癌调强放射治疗（intensity-modulated radiation therapy，IMRT）中的应用价值。方法选取食管上段癌患者68例，随机分为2组各34例，A 组 IMRT 前行颈部彩色超声检查，发现有淋巴结转移的作为累及野治疗，B 组不行彩色超声检查，均采用5个野 IMRT。结果放射治疗结束后2组总有效率比较差异无统计学意义（P ＞0．05）。2组1年和2年生存率差异无统计学意义（P ＞0．05）。A 组3年生存率高于 B 组，差异有统计学意义（P ＜0．05）。放射治疗不良反应主要以1～2级为主，2组不良反应发生率比较差异无统计学意义（P ＞0．05）。A 组病死率低于 B 组，差异有统计学意义（P ＜0．05）。结论在食管上段癌的 IMRT 前颈部彩色超声检查作为颈部照射野的依据，可提高患者的3年生存率，且近期疗效好，不良反应可耐受。
목적：관찰경부채색초성재식관상단암조강방사치료（intensity-modulated radiation therapy，IMRT）중적응용개치。방법선취식관상단암환자68례，수궤분위2조각34례，A 조 IMRT 전행경부채색초성검사，발현유림파결전이적작위루급야치료，B 조불행채색초성검사，균채용5개야 IMRT。결과방사치료결속후2조총유효솔비교차이무통계학의의（P ＞0．05）。2조1년화2년생존솔차이무통계학의의（P ＞0．05）。A 조3년생존솔고우 B 조，차이유통계학의의（P ＜0．05）。방사치료불량반응주요이1～2급위주，2조불량반응발생솔비교차이무통계학의의（P ＞0．05）。A 조병사솔저우 B 조，차이유통계학의의（P ＜0．05）。결론재식관상단암적 IMRT 전경부채색초성검사작위경부조사야적의거，가제고환자적3년생존솔，차근기료효호，불량반응가내수。
Objective To investigate the use of carotid ultrasonography in the intensity-modulated radiation therapy(IMRT)of upper esophageal cancer.Methods Sixty-eight patients with upper esophageal cancer were divided into group A(experimental group,34 cases)and group B(control group,34 cases).In group A,the areas were treated by IMRT on condition that lymph nodes metastasis was found.Both groups were performed by IMRT through a 5 field IMRT plan. Results There were no significant differences between two groups in total effective rate(P >0.05).The first and second year′s survival rate in group A and group B were no significant differences(P >0.05).The 3 years'rate in group A was distinctly higher than that in group B(P <0.05).The side effects of radiotherapy were mainly classified into grade 1 and 2.In addition,no significant differences were noted between the two groups.The fatality rate in group A was remarkably lower than that in group B(P < 0.05).Conclusion Carotid ultrasonography can be used as a basis of neck irradiation in IMRT of upper esophageal carcinoma,which can improve the 3 years′ survival rates with satisfactory recent curative effect and several tolerable toxic side effects.