CAJ | 학술논문

目的：探讨经皮肝穿刺胆道射频消融联合支架植入术治疗恶性胆道梗阻引起的黄疸的安全性和有效性。方法回顾性收集18例行经皮肝穿刺胆道射频消融联合金属支架植入术的恶性胆道梗阻患者的临床资料。分析近期的疗效及并发症。结果经联合治疗后2 d,患者除白蛋白下降外,其他主要肝功能指标均显著改善,术后1月肝功能进一步改善,白蛋白升至治疗前水平。18例患者均未发生肝功能不全,无患者在30 d 内死亡。严重并发症中,胆管穿孔0例(0.0%),胆漏1例(5.5%),出血1例(5.5%),术后胰腺炎0例(0.0%)；轻微并发症中,胆道感染3例(16.7%),疼痛7例(38.9%),呕吐3例(16.7%)。结论经皮肝穿刺胆管内射频消融联合支架植入术治疗恶性胆道梗阻是安全有效的。
목적：탐토경피간천자담도사빈소융연합지가식입술치료악성담도경조인기적황달적안전성화유효성。방법회고성수집18례행경피간천자담도사빈소융연합금속지가식입술적악성담도경조환자적림상자료。분석근기적료효급병발증。결과경연합치료후2 d,환자제백단백하강외,기타주요간공능지표균현저개선,술후1월간공능진일보개선,백단백승지치료전수평。18례환자균미발생간공능불전,무환자재30 d 내사망。엄중병발증중,담관천공0례(0.0%),담루1례(5.5%),출혈1례(5.5%),술후이선염0례(0.0%)；경미병발증중,담도감염3례(16.7%),동통7례(38.9%),구토3례(16.7%)。결론경피간천자담관내사빈소융연합지가식입술치료악성담도경조시안전유효적。
Objective To investigate the safety and efficacy of percutaneous intraductal radiofrequency ablation in combination with stent implantation for treatment of jaundice caused by biliary malignance.Methods The clinical data of malignant biliary ob-struction in 18 patients were collected retrospectively who were treated by percutaneous intraductal radiofrequency ablation in combi-nation with stent implantation.Results On two days after combined therapy,except for the decreased albumin,other major indica-tors of liver function were significantly recovered.At 1 month after therapy,the liver function further improved with normal level of albumin.No liver function insufficiency occurred in all patients,and no patient died within 30 days.Few serious complications inclu-ding bile leakage in 1 (5.5%)and hemorrhage in 1 (5.5%)and some slight complications including biliary tract infection in 3 (1 6.7%),pain in 7 (38.9%)and vomit in 3 (1 6.7%)were observed.Conclusion Percutaneous transhepatic radiofrequency ablation combined with stent implantation is a safe and effective treatment for malignant biliary obstruction.