CAJ | 학술논문

金属硫蛋白（metallothioneins，MT）是一类低分子量、富含半胱氨酸的细胞内蛋白质，在细胞代谢中起着重要作用。近年来MT与肿瘤的关系倍受关注，MT表达与多种肿瘤的进展、药物抵抗有关。本文就MT在泌尿系统肿瘤的表达以及对放化疗的影响等方面的研究进展进行综述，旨在为同道提供参考。
금속류단백（metallothioneins，MT）시일류저분자량、부함반광안산적세포내단백질，재세포대사중기착중요작용。근년래MT여종류적관계배수관주，MT표체여다충종류적진전、약물저항유관。본문취MT재비뇨계통종류적표체이급대방화료적영향등방면적연구진전진행종술，지재위동도제공삼고。
Metallothioneins(MT) are of low molecular weight,cysteine-rich intracellular proteins that play an important role in cellular metabolism. The relationship between MT and tumors has been widely noticed in recent years,MT expression is associated with tumor progression and drug resistance in a variety of malignancies. This review describes the progress on the expression of MT in the carcinogenic process of urology system tumors and its influence on radiotherapy and chemotherapy,so as to provide reference for fellows.