CAJ | 학술논문

着斑激酶（focal adhesion kinase，FAK）是一种细胞质内的蛋白酪氨酸激酶（protein tyrosine kinase，PTK），因其与细胞粘附功能密切相关而得名。近年来，人们对FAK的了解逐渐深入，国内外大量研究表明FAK在多种肿瘤组织中表达增高，并与肿瘤的多个过程有着密切的关系。FAK已经成为新的肿瘤治疗靶点之一，为肿瘤的治疗带来新的方法和希望。
착반격매（focal adhesion kinase，FAK）시일충세포질내적단백락안산격매（protein tyrosine kinase，PTK），인기여세포점부공능밀절상관이득명。근년래，인문대FAK적료해축점심입，국내외대량연구표명FAK재다충종류조직중표체증고，병여종류적다개과정유착밀절적관계。FAK이경성위신적종류치료파점지일，위종류적치료대래신적방법화희망。
Focal adhesion kinase (FAK), a type of protein tyrosine kinase in the cytoplasm, is highly expressed in many types of malignant tumors. FAK is named as such because of its close relationship with the cell adhesion function. Recent studies show that FAK is expressed in many tumor cells and has a definite relationship with cancer progress, metastasis, and prognosis. Accordingly, FAK has become one of the new tumor therapeutic targets that will bring new methods for tumor therapy.