临床心身疾病杂志
臨床心身疾病雜誌
림상심신질병잡지
JOURNAL OF CLINICAL PSYCHOSOMATIC DISEASES
2015年
1期
45-47,69
,共4页
冠心病%支架植入%草酸艾司西酞普兰%放松训练%焦虑%抑郁%汉密顿抑郁量表%汉密顿焦虑量表%生活质量量表%副反应量表
冠心病%支架植入%草痠艾司西酞普蘭%放鬆訓練%焦慮%抑鬱%漢密頓抑鬱量錶%漢密頓焦慮量錶%生活質量量錶%副反應量錶
관심병%지가식입%초산애사서태보란%방송훈련%초필%억욱%한밀돈억욱량표%한밀돈초필량표%생활질량량표%부반응량표
CHD%stent implantation%escitalopram oxalate%relaxation training%anxiety%depression%HAMD%HAMA%SF-36%TESS
目的：探讨放松训练联合草酸艾司西酞普兰对冠心病支架植入术后患者伴发焦虑抑郁情绪的临床疗效和安全性以及对生活质量的影响。方法将65例冠心病冠脉支架植入术后伴焦虑抑郁患者随机分为两组，均予以冠心病常规治疗及放松训练，研究组在此基础上联合草酸艾司西酞普兰治疗，观察8周。采用汉密顿焦虑量表、汉密顿抑郁量表评定焦虑抑郁情绪，生活质量量表评定生活质量，副反应量表评定不良反应。结果治疗后两组汉密顿焦虑量表、汉密顿抑郁量表评分较治疗前显著下降（P＜0．01），研究组较对照组下降更显著（P＜0．01）；研究组生活质量量表的4个领域、对照组1个领域评分较治疗前显著升高（P＜0．01），研究组5个领域评分显著高于对照组（P＜0．01）。治疗过程中两组不良反应均轻微，各项实验室检查均无异常改变。结论放松训练联合草酸艾司西酞普兰能显著改善冠心病冠脉支架植入术患者伴发的焦虑抑郁情绪，提高患者的生活质量，且安全性高，优于单用放松训练治疗。
目的：探討放鬆訓練聯閤草痠艾司西酞普蘭對冠心病支架植入術後患者伴髮焦慮抑鬱情緒的臨床療效和安全性以及對生活質量的影響。方法將65例冠心病冠脈支架植入術後伴焦慮抑鬱患者隨機分為兩組，均予以冠心病常規治療及放鬆訓練，研究組在此基礎上聯閤草痠艾司西酞普蘭治療，觀察8週。採用漢密頓焦慮量錶、漢密頓抑鬱量錶評定焦慮抑鬱情緒，生活質量量錶評定生活質量，副反應量錶評定不良反應。結果治療後兩組漢密頓焦慮量錶、漢密頓抑鬱量錶評分較治療前顯著下降（P＜0．01），研究組較對照組下降更顯著（P＜0．01）；研究組生活質量量錶的4箇領域、對照組1箇領域評分較治療前顯著升高（P＜0．01），研究組5箇領域評分顯著高于對照組（P＜0．01）。治療過程中兩組不良反應均輕微，各項實驗室檢查均無異常改變。結論放鬆訓練聯閤草痠艾司西酞普蘭能顯著改善冠心病冠脈支架植入術患者伴髮的焦慮抑鬱情緒，提高患者的生活質量，且安全性高，優于單用放鬆訓練治療。
목적：탐토방송훈련연합초산애사서태보란대관심병지가식입술후환자반발초필억욱정서적림상료효화안전성이급대생활질량적영향。방법장65례관심병관맥지가식입술후반초필억욱환자수궤분위량조，균여이관심병상규치료급방송훈련，연구조재차기출상연합초산애사서태보란치료，관찰8주。채용한밀돈초필량표、한밀돈억욱량표평정초필억욱정서，생활질량량표평정생활질량，부반응량표평정불량반응。결과치료후량조한밀돈초필량표、한밀돈억욱량표평분교치료전현저하강（P＜0．01），연구조교대조조하강경현저（P＜0．01）；연구조생활질량량표적4개영역、대조조1개영역평분교치료전현저승고（P＜0．01），연구조5개영역평분현저고우대조조（P＜0．01）。치료과정중량조불량반응균경미，각항실험실검사균무이상개변。결론방송훈련연합초산애사서태보란능현저개선관심병관맥지가식입술환자반발적초필억욱정서，제고환자적생활질량，차안전성고，우우단용방송훈련치료。
Objective To explore the efficacy and safety of relaxation training plus escitalopram in anxiety‐depression emotion of coronary heart disease (CHD) patients undergoing stent implantation and effect on quality of life .Methods Sixty‐five CHD patients undergoing stent implantation who were accompanied with anxiety‐depression emotion were randomly assigned to two groups ,both groups received CHD routine treatment and relaxation training ,on this basis research group was plus escitalopram oxalate for 8 weeks . Anxiety‐depression emotions were assessed with the Hamilton Anxiety Scale (HAMA) and Hamilton De‐pression Scale(HAMD) ,qualities of life with the Short Form 36 Health Survey Questionnaire (SF‐36) , and adverse reactions with the Treatment Emergent Symptom Scale (TESS) .Results The HAMD and HAMA scores of both groups lowered more significantly after treatment compared with pretreatment (P<0 .01) ,so did those in research than control group (P<0 .01);4 domain scores of the SF‐36 in research group and 1 domain score in control group heightened more significantly after treatment (P<0 .01) ,so did 5 domain scores in research than control group (P<0 .01) .Adverse reactions of both groups were mild , all laboratory examinations had no abnormal changes .Conclusion Relaxation training plus escitalopram oxalate could improve the anxiety‐depression emotions of CHD patients undergoing stent implantation and quality of life and has higher safety compared with single relaxation training .
