CAJ | 학술논문

溃疡性结肠炎( ulcerative colitis,UC)是一种以慢性肠道炎症为特征的炎症性肠病。 UC的发病机制还未完全明确,其发生与免疫、遗传、环境及感染因素有关,细胞因子在UC等炎症性肠病中起到重要作用。白细胞介素( interleukin,IL)是细胞因子中最主要的具有多种生物活性的一组淋巴因子,并在免疫细胞的发育、分化、免疫应答等过程中有重要调节作用。目前研究发现很多IL在UC的发病中起重要作用。本文对在UC中起重要作用的IL作一概述。
궤양성결장염( ulcerative colitis,UC)시일충이만성장도염증위특정적염증성장병。 UC적발병궤제환미완전명학,기발생여면역、유전、배경급감염인소유관,세포인자재UC등염증성장병중기도중요작용。백세포개소( interleukin,IL)시세포인자중최주요적구유다충생물활성적일조림파인자,병재면역세포적발육、분화、면역응답등과정중유중요조절작용。목전연구발현흔다IL재UC적발병중기중요작용。본문대재UC중기중요작용적IL작일개술。
Ulcerative colitis ( UC) is one kind of inflammatory bowel diseases charactered by chronic inflammation of colon. The pathogenesis of UC is not clear, immunity, heredity, environment and infection may participate in occurence of UC, cytokines play an important role in UC and other inflammation bowel diseases. Interleukin ( IL) , the most im-portant member of cytokines, is a group of lymphokine with multi-biological activity, and regulates growth, differentia-tion, immune response of immune cell. The present studies illustrate ILs play important roles in pathogenesis of UC. This paper is a review of ILs relate to UC.