CAJ | 학술논문

目的：探讨原发性消化道非霍奇金淋巴瘤( primary gastrointestinal non-Hodgkin’ s lymphoma,PGI-NHL)的临床特征和预后。方法回顾性分析新疆石河子大学医学院第一附属医院2006年1月-2012年12月收治的31例经病理确诊的PGI-NHL患者的临床资料。结果临床表现包括纳差、腹痛、腹胀、呕吐、黑便、发热、乏力、消瘦等,其中最主要临床表现为纳差、腹胀。病理分型均为B细胞性淋巴瘤。 Kaplan-Meler分析,Log Rank比较显示,性别、年龄、是否行手术、是否有B组症状与生存无显著相关性( P>0.05),分期与生存有显著相关性(P<0.05)。结论 PGI-NHL分期发现越早预后越好,因此,PGI-NHL的早期诊断有重要的临床意义。
목적：탐토원발성소화도비곽기금림파류( primary gastrointestinal non-Hodgkin’ s lymphoma,PGI-NHL)적림상특정화예후。방법회고성분석신강석하자대학의학원제일부속의원2006년1월-2012년12월수치적31례경병리학진적PGI-NHL환자적림상자료。결과림상표현포괄납차、복통、복창、구토、흑편、발열、핍력、소수등,기중최주요림상표현위납차、복창。병리분형균위B세포성림파류。 Kaplan-Meler분석,Log Rank비교현시,성별、년령、시부행수술、시부유B조증상여생존무현저상관성( P>0.05),분기여생존유현저상관성(P<0.05)。결론 PGI-NHL분기발현월조예후월호,인차,PGI-NHL적조기진단유중요적림상의의。
Objective To investigate the clinical manifestaions and prognosis of patients with primary gastrointestinal non-Hodgkin’ s lymphoma ( PGI-NHL) . Methods Chinical datas of 31 cases with PGI-NHL in the First Affiliated Hos-pital of Shihezi University School of Medicine. from Jan. 2006 to Dec. 2012 were retrospectively analyzed. Results The major clinical symptoms of PGI-NHL were anorexia, abdominal pain, abdominal distention, vomiting, melena, fever, fatigue, weight loss, etc, and the most important clinical manifestations were anorexia, abdominal distension. All the cases immune phenotype were B-cell lineage. Kaplan-Meler analysis showed that there was no significant correlation be-tween gender, age, whether surgery, whether had B symtoms and survival (P >0. 05). The stage of PGI-NHL was closely correlated to the survival (P<0. 05). Conclusion The earlier diagnosis the stage of PGI-NHL, the better prog-nosis, it has important clinical significant.