中国药物评价
中國藥物評價
중국약물평개
Chinese Journal of Drug Evaluation
2014年
6期
338-340
,共3页
张路%王春艳%李民%赵婷婷%李士栋%张淹
張路%王春豔%李民%趙婷婷%李士棟%張淹
장로%왕춘염%리민%조정정%리사동%장엄
复方阿胶颗粒%子宫平滑肌%扭体反应%痛经
複方阿膠顆粒%子宮平滑肌%扭體反應%痛經
복방아효과립%자궁평활기%뉴체반응%통경
Fu Fang E Jiao Ke Li%Uterine smooth muscle%Writhing response%Menorrhalgia
目的:通过复方阿胶颗粒对缩宫素致大鼠痛经样反应的影响,探讨复方阿胶颗粒缓解经期痛经症状的机制。方法:观察复方阿胶颗粒对缩宫素所致的体外子宫平滑肌剧烈收缩的影响,及其对痛经痉挛的抑制作用。结果:复方阿胶颗粒显著抑制缩宫素所致的体外子宫平滑肌的收缩,明显减少痛经大鼠扭体反应次数、延长发生扭体的潜伏期。结论:复方阿胶颗粒具有缓解经期痛经时痉挛及疼痛的作用。
目的:通過複方阿膠顆粒對縮宮素緻大鼠痛經樣反應的影響,探討複方阿膠顆粒緩解經期痛經癥狀的機製。方法:觀察複方阿膠顆粒對縮宮素所緻的體外子宮平滑肌劇烈收縮的影響,及其對痛經痙攣的抑製作用。結果:複方阿膠顆粒顯著抑製縮宮素所緻的體外子宮平滑肌的收縮,明顯減少痛經大鼠扭體反應次數、延長髮生扭體的潛伏期。結論:複方阿膠顆粒具有緩解經期痛經時痙攣及疼痛的作用。
목적:통과복방아효과립대축궁소치대서통경양반응적영향,탐토복방아효과립완해경기통경증상적궤제。방법:관찰복방아효과립대축궁소소치적체외자궁평활기극렬수축적영향,급기대통경경련적억제작용。결과:복방아효과립현저억제축궁소소치적체외자궁평활기적수축,명현감소통경대서뉴체반응차수、연장발생뉴체적잠복기。결론:복방아효과립구유완해경기통경시경련급동통적작용。
Objective:To explore the mechanism of fu fang e jiao ke li( FFEJ) relieve menstrual symptoms of dysmenorrheal by FFEJ on oxytocin induced dysmenorrhea-like reaction.Methods:To observe FFEJ on oxytocin induced uterine smooth muscle in vitro contrac-tion of violent,and inhibition on spasmodic dysmenorrhea.Results:FFEJ could strongly inhibit the autonomic contraction activities of free ratuterus in those uterine smooth muscle in vitro induced by oxytocin.It also could significantly decrease the torsion times and prolong the incubation period writhing.Conclusion:FFEJ can relieve spasmodic dysmenorrheal and pain.