CAJ | 학술논문

目的：探讨甲状腺功能亢进患者动脉粥样硬化情况，以了解甲状腺功能亢进与动脉粥样硬化关系。方法选择甲亢患者72例与对照组63例进行颈动脉超声及血液生化检查，观察2组的CIMT、ET、NO及CRP情况。结果 CIMT在45岁以上甲亢组明显高于45岁以下甲亢组与对照组，差异具有统计学意义（P<0.05）；CIMT在45岁以上甲亢组及对照组中差异无统计学意义（P>0．05）。ET、NO及CRP水平在甲亢组中高于正常组，差异具有统计学意义（P<0.05）。结论甲亢可引起血管内皮损害，发生动脉粥样硬化的风险增高。
목적：탐토갑상선공능항진환자동맥죽양경화정황，이료해갑상선공능항진여동맥죽양경화관계。방법선택갑항환자72례여대조조63례진행경동맥초성급혈액생화검사，관찰2조적CIMT、ET、NO급CRP정황。결과 CIMT재45세이상갑항조명현고우45세이하갑항조여대조조，차이구유통계학의의（P<0.05）；CIMT재45세이상갑항조급대조조중차이무통계학의의（P>0．05）。ET、NO급CRP수평재갑항조중고우정상조，차이구유통계학의의（P<0.05）。결론갑항가인기혈관내피손해，발생동맥죽양경화적풍험증고。
Objective To investigate the characteristics of carotid atherosclerotic lesions in patients with hyperthyroidism.Methods 72 patients with hyperthyroidism ( hyperthyroidism group) and 63 cases of healthy volunteers ( control group) were investigated, the changes of CIMT, ET, NO, CRP were observed.Results CIMT in hyperthyroidism group with above 45 years old was higher than those of the hyperthyroidism group and control group with Less than 45 years old. The levels of ET, NO, CRP in hyperthyroidism group were higher than those of the control group.Conclusion Hyperthyroidism is associated with endothelial damage and increase the risk of atherosclerosis.