CAJ | 학술논문

目的：实验旨在观察磁场干预对大鼠外周神经损伤后神经瘢痕形成过程的影响。方法选用清洁SD大鼠80只，均对其行左侧坐骨神经卡压术，造成神经损伤，术后随机分4组，对照组1组，实验组3组，实验组分别给予0.2 mT、0.6 mT、1.5 mT强度磁疗，60 min/d，21 d后测量坐骨神经功能指数（SFI），之后取材，进行Ⅰ型胶原纤维免疫组织化学染色、透射电镜观察，并对实验资料进行统计学处理。结果实验组较对照组神经功能指数更接近正常；神经损伤处Ⅰ型胶原纤维增生少，髓鞘板层厚且走行规则。结论磁场干预可以明显抑制神经瘢痕的形成，促进神经再生及其功能恢复。
목적：실험지재관찰자장간예대대서외주신경손상후신경반흔형성과정적영향。방법선용청길SD대서80지，균대기행좌측좌골신경잡압술，조성신경손상，술후수궤분4조，대조조1조，실험조3조，실험조분별급여0.2 mT、0.6 mT、1.5 mT강도자료，60 min/d，21 d후측량좌골신경공능지수（SFI），지후취재，진행Ⅰ형효원섬유면역조직화학염색、투사전경관찰，병대실험자료진행통계학처리。결과실험조교대조조신경공능지수경접근정상；신경손상처Ⅰ형효원섬유증생소，수초판층후차주행규칙。결론자장간예가이명현억제신경반흔적형성，촉진신경재생급기공능회복。
Objective To observe how magnetic field interference effect on nerve scar formation after nerve injury in rats.Methods 80 SD rats were implemented left sciatic nerve entrapment surgery, with nerve damaged. After surgery, the rats were randomly divided into four groups: 1 control group and 3 experimental groups. Experimental groups were respectively given 0.2 mT’s, 0.6 mT’s, and 1.5 mT’s intensity magnetic therapy, 60 min/d. Sciatic nerve function index measurement (SFI) was tested in 21 days. After drawn, the samples were applied, type collagen ifbers immunohistochemical staining, transmission electron microscope and experimental data statistics processing were performed.Results Compared with the control group, the experimental group was closer to normal in nerve function index, with less, type collagen ifbers hyperplasia in Nerve lesions, thicker myelin sheath and line rules walking.Conclusion Magnetic field interference can significantly inhibit scar formation, promote nerve regeneration and functional recovery.