CAJ | 학술논문

旨在探讨类猪圆环病毒P1感染对PK15细胞自噬的影响。将同一批PK15细胞分成对照组和感染组，感染组在类猪圆环病毒P1感染PK15细胞后14，24，48 h分别收集细胞，对照组也在同样时间收获，用透射电镜观察自噬现象的发生。结果表明，与对照组相比，感染组PK15细胞内出现典型自噬形态学变化。揭示类猪圆环病毒P1能诱导PK15细胞发生自噬，但细胞发生自噬的相关信号传导通路还有待进一步研究。
지재탐토류저원배병독P1감염대PK15세포자서적영향。장동일비PK15세포분성대조조화감염조，감염조재류저원배병독P1감염PK15세포후14，24，48 h분별수집세포，대조조야재동양시간수획，용투사전경관찰자서현상적발생。결과표명，여대조조상비，감염조PK15세포내출현전형자서형태학변화。게시류저원배병독P1능유도PK15세포발생자서，단세포발생자서적상관신호전도통로환유대진일보연구。
The research is to study the autophagy induced by porcine circovirus-like virus P1.PK15 cells(Both P1 infection and control group ) were collected at various time periods (14,24,48 h) and used to detect autophagy by transmission electron microscopy .Compared with the control groups ,the typical morphological features of autoph-agy was detected in PK-15 cells infected with P1.The result suggests that porcine circovirus-like virus P1 can in-duce the autophagy of PK-15 cells.