基层医学论坛
基層醫學論罈
기층의학론단
PUBLIC MEDICAL FORUM MAGAZINE
2015年
5期
580-581
,共2页
泪囊鼻腔吻合术%丝裂霉素C%疗效%安全性
淚囊鼻腔吻閤術%絲裂黴素C%療效%安全性
루낭비강문합술%사렬매소C%료효%안전성
Dacryocystorhinostomy%Mitomycin C%Curative effect%Safety
目的：探讨丝裂霉素C（MMC）应用于泪囊鼻腔吻合术（dacryocystorhinostomy，DCR）的疗效。方法将泪道阻塞78眼随机分为对照组和治疗组，治疗组（A组）在常规DCR术中用含有0.02%MMC的棉片置放于骨切孔区鼻黏膜和泪囊黏膜上5 min；对照组（B组）则采用常规DCR手术。结果随访6个月~9个月，术后1，3个月A组治愈率分别为100%，97.5%，B组分别为81.6%，76.3%，6，9个月A组治愈率均为92.5%， B组均为65.8%，2组比较差异有统计学意义（P<0.05），且A组无手术并发症发生。结论在DCR手术中应用MMC是一种能够显著提高治疗效果且安全有效的辅助措施。
目的：探討絲裂黴素C（MMC）應用于淚囊鼻腔吻閤術（dacryocystorhinostomy，DCR）的療效。方法將淚道阻塞78眼隨機分為對照組和治療組，治療組（A組）在常規DCR術中用含有0.02%MMC的棉片置放于骨切孔區鼻黏膜和淚囊黏膜上5 min；對照組（B組）則採用常規DCR手術。結果隨訪6箇月~9箇月，術後1，3箇月A組治愈率分彆為100%，97.5%，B組分彆為81.6%，76.3%，6，9箇月A組治愈率均為92.5%， B組均為65.8%，2組比較差異有統計學意義（P<0.05），且A組無手術併髮癥髮生。結論在DCR手術中應用MMC是一種能夠顯著提高治療效果且安全有效的輔助措施。
목적：탐토사렬매소C（MMC）응용우루낭비강문합술（dacryocystorhinostomy，DCR）적료효。방법장루도조새78안수궤분위대조조화치료조，치료조（A조）재상규DCR술중용함유0.02%MMC적면편치방우골절공구비점막화루낭점막상5 min；대조조（B조）칙채용상규DCR수술。결과수방6개월~9개월，술후1，3개월A조치유솔분별위100%，97.5%，B조분별위81.6%，76.3%，6，9개월A조치유솔균위92.5%， B조균위65.8%，2조비교차이유통계학의의（P<0.05），차A조무수술병발증발생。결론재DCR수술중응용MMC시일충능구현저제고치료효과차안전유효적보조조시。
Objective To test the mitomycin C(MMC) used in dacryocystorhinostomy(Dacryocystorhinostomy, DCR)in order to improve the operation effect of DCR effect. Methods 78 eyes with lacrimal duct obstruction were randomly divided into the treatment group and the control group,the treatment group (group A)cotton sheet is provided with 0.02%MMC in conventional DCR surgery for bone hole cutting area of the nasal mucosa and lacrimal sac mucosa for 5 minutes. The control group(group B)with conventional DCR operation. Results all patients were followed up for 6-9 months after operation,1-3 months,In A group,the cure rate was 100%,B group were 89.5%,81.5%,6-9 months:in A group,the cure rate was 95%,B group were 73.7%,71.1%,there was significant difference between two groups (P '0. 05),A group was significantly higher than that in group B,and no operation complication. Conclusion The application of MMC in DCR operation is an effective auxiliary measure and is significantly improving the therapeutic effect and safety.
