CAJ | 학술논문

目的：探究铝碳酸镁及多潘立酮治疗胆汁反流性胃炎临床效果。方法随机选取2012年10月～2013年10月治疗70例胆汁反流性胃炎患者，分为实验组和对照组两组，每组患者35例。其中，前一组采用铝碳酸镁及多潘立酮治疗，而后一组单用多潘立酮治疗，治疗后，对比两组的治疗效果、症状指标与胃内24 h时胆汁反流情况。结果实验组的总有效率为94.28％，对照组的总有效率为77.14％，差异显著，具有统计学意义（ P＜0.05）。但治疗前后，观察组患者症状积分明显不明显，无统计学意义（P＞0.05），治疗后2、4周，患者出现上腹胀、呕吐等临床反应，较治疗前，积分显著降低，有统计学意义（ P＜0.05）。治疗后24 h，胃内胆汁反流总时间、次数、持续大于5 min次数显著下降（P＜0.01），无统计学意义（P＞0.05）。结论多潘立酮及铝碳酸镁治疗胆汁反流性胃炎，较单用多潘立酮的临床效果显著，临床症状改善，胆汁反流减少。
목적：탐구려탄산미급다반립동치료담즙반류성위염림상효과。방법수궤선취2012년10월～2013년10월치료70례담즙반류성위염환자，분위실험조화대조조량조，매조환자35례。기중，전일조채용려탄산미급다반립동치료，이후일조단용다반립동치료，치료후，대비량조적치료효과、증상지표여위내24 h시담즙반류정황。결과실험조적총유효솔위94.28％，대조조적총유효솔위77.14％，차이현저，구유통계학의의（ P＜0.05）。단치료전후，관찰조환자증상적분명현불명현，무통계학의의（P＞0.05），치료후2、4주，환자출현상복창、구토등림상반응，교치료전，적분현저강저，유통계학의의（ P＜0.05）。치료후24 h，위내담즙반류총시간、차수、지속대우5 min차수현저하강（P＜0.01），무통계학의의（P＞0.05）。결론다반립동급려탄산미치료담즙반류성위염，교단용다반립동적림상효과현저，림상증상개선，담즙반류감소。
O bjective To explore the hydrotalcite and domperidone in treating bile reflux gastritis clinical effect.Meth ods Randomly selected in 2012October ~2013 year in October in our hospital for treatment of 70 cases of bile reflux gastritis patients , divided into experimental group and control group two groups , 35 cases each group of pa-tients.Among them , the hydrotalcite and domperidone treatment before a group of a group , and then treated with domp-eridone , single treatment , effect of treatment , compared two groups of symptoms and gastric 24 h bile reflux.Results In the experimental group , the total efficiency is 94.28%, control group in the total efficiency is 77.14%, significantly dif-ferent, with statistical significance (P<0.05).But before and after treatment,the patients in observation group were not obvious symptoms, no statistical significance (P>0.05), 2, 4 weeks after the treatment, patients with abdominal distention , vomiting and other clinical response , compared with before treatment , scores decreased significantly , with statistical significance (P<0.05).After treatment with 24h, intragastric bile reflux time, frequency, duration more than 5min times decreased significantly (P<0.01), no statistical significance (P>0.05).Conclusions Domperidone and Hydrotalcid on bile reflux gastritis , than single use of clinical effect of domperidone significantly , improve the clini-cal symptoms , bile reflux reduction.