航空航天医学杂志
航空航天醫學雜誌
항공항천의학잡지
AEROSPACE MEDICINE
2015年
1期
20-21
,共2页
阿司匹林%脑梗死急性期%剂量
阿司匹林%腦梗死急性期%劑量
아사필림%뇌경사급성기%제량
aspirin%cerebral infarction%dose
目的：系统评价不同剂量阿司匹林用于脑梗死急性期的临床效果。方法选取神经内科近1年来收治的脑梗死急性期的患者80例，年龄38～65岁随机分成试验组与对照组，两组均为40例。试验组在治疗时接受大剂量阿司匹林（300 mg）疗法，对照组接受小剂量阿司匹林（100 mg）法。观察及对比两组临床疗效。结果在80例患者中，大剂量阿司匹林疗法有效率91.03％，小剂量阿司匹林法的有效率为83.67％。经χ2检验两两比较，大剂量阿司匹林疗法的有效率均高于单独用小剂量阿司匹林（100 mg）法，P值为0.042。大剂量阿司匹林疗法组无论是在血小板开始下降时间，还是在血小板达到最低值时间和梗塞病症得到控制时间均明显低于小剂量阿司匹林（100 mg）法组，并且上述数值两组之间的差异有统计学意义（ P值分别为0.025、0.031和0.043）。结论大剂量阿司匹林疗法对于脑梗死急性期患者具有较好的临床疗效，较小剂量阿司匹林法对脑梗死急性期抗血管形成功能具有较好的临床治疗效果。
目的：繫統評價不同劑量阿司匹林用于腦梗死急性期的臨床效果。方法選取神經內科近1年來收治的腦梗死急性期的患者80例，年齡38～65歲隨機分成試驗組與對照組，兩組均為40例。試驗組在治療時接受大劑量阿司匹林（300 mg）療法，對照組接受小劑量阿司匹林（100 mg）法。觀察及對比兩組臨床療效。結果在80例患者中，大劑量阿司匹林療法有效率91.03％，小劑量阿司匹林法的有效率為83.67％。經χ2檢驗兩兩比較，大劑量阿司匹林療法的有效率均高于單獨用小劑量阿司匹林（100 mg）法，P值為0.042。大劑量阿司匹林療法組無論是在血小闆開始下降時間，還是在血小闆達到最低值時間和梗塞病癥得到控製時間均明顯低于小劑量阿司匹林（100 mg）法組，併且上述數值兩組之間的差異有統計學意義（ P值分彆為0.025、0.031和0.043）。結論大劑量阿司匹林療法對于腦梗死急性期患者具有較好的臨床療效，較小劑量阿司匹林法對腦梗死急性期抗血管形成功能具有較好的臨床治療效果。
목적：계통평개불동제량아사필림용우뇌경사급성기적림상효과。방법선취신경내과근1년래수치적뇌경사급성기적환자80례，년령38～65세수궤분성시험조여대조조，량조균위40례。시험조재치료시접수대제량아사필림（300 mg）요법，대조조접수소제량아사필림（100 mg）법。관찰급대비량조림상료효。결과재80례환자중，대제량아사필림요법유효솔91.03％，소제량아사필림법적유효솔위83.67％。경χ2검험량량비교，대제량아사필림요법적유효솔균고우단독용소제량아사필림（100 mg）법，P치위0.042。대제량아사필림요법조무론시재혈소판개시하강시간，환시재혈소판체도최저치시간화경새병증득도공제시간균명현저우소제량아사필림（100 mg）법조，병차상술수치량조지간적차이유통계학의의（ P치분별위0.025、0.031화0.043）。결론대제량아사필림요법대우뇌경사급성기환자구유교호적림상료효，교소제량아사필림법대뇌경사급성기항혈관형성공능구유교호적림상치료효과。
Objective To evaluate the clinical effect of different doses of aspirin for acutecerebral infarc-tion.Methods 80 acute cerebral infarction patients were chosen in our hospitaldepartment of internal medicine nerve during the past 1 years, age 38~65 years old were randomly divided into experimental group and control group , two groups for 40 cases.The experimental group received a large dose of aspirin in the treatment (300 mg) therapy, the con-trol group received low dose aspirin (100 mg) method.Observation and comparison of twogroups of clinical curative effect.Results In 80 patients, high-dose aspirin therapy efficiency of 91.03%, small dose aspirin method efficiency is 83.67%.The X2 test is two two , the effective rate of large dose of aspirin therapy was higher than the single use of low-dose aspirin (100 mg) method, the P value is 0.042.High dose aspirin therapy group both began to decline in platelet,and reached the minimum time and infarction disease control time was significantly lower than that of low dose aspirin on platelet (100 mg) group, and the difference was statistically significantbetween the two groups the values ( P values were 0.025 , 0.031 and 0.043 ).Conclusions High dose aspirin therapy has good clinical efficacy in patients with cerebral infarction in acute stage ,small dose of aspirin in acute period of cerebral infarction anti angiogenesis func -tion has abetter clinical therapeutic effect.
