CAJ | 학술논문

目的：调查炼化社区原发性高血压及高血压合并糖尿病患者血浆同型半胱氨酸、超敏C反应蛋白水平，探讨相关的健康教育对策。方法选取炼化社区已纳入我院慢病管理科的高血压患者为病例组，以本社区健康人群为健康对照组，分析高血压各亚组、高血压合并糖尿病组与健康对照组之间的血浆同型半胱胺酸、超敏C反应蛋白值的差异。结果高血压各亚组间的血浆同型半胱胺酸、超敏C反应蛋白水平、高检出率及同型半胱酸的边缘升高率均随着高血压级别升高逐渐增高；高血压合并糖尿病患者的血浆同型半胱胺酸和超敏C反应蛋白水平、高检出率及同型半胱胺酸的边缘升高率均高于单纯性高血压组，单纯性高血压组高于健康对照组，差异有统计学意义（P<0.01）。结论对重点人群定期进行血浆同型半胱胺酸、超敏C反应蛋白动态水平的监测，动态评估病情发生发展的严重程度，制定健康教育对策，以做到早发现、早预防，减少心脑血管不良事件的发生，降低脑卒中的发生与发展。
목적：조사련화사구원발성고혈압급고혈압합병당뇨병환자혈장동형반광안산、초민C반응단백수평，탐토상관적건강교육대책。방법선취련화사구이납입아원만병관이과적고혈압환자위병례조，이본사구건강인군위건강대조조，분석고혈압각아조、고혈압합병당뇨병조여건강대조조지간적혈장동형반광알산、초민C반응단백치적차이。결과고혈압각아조간적혈장동형반광알산、초민C반응단백수평、고검출솔급동형반광산적변연승고솔균수착고혈압급별승고축점증고；고혈압합병당뇨병환자적혈장동형반광알산화초민C반응단백수평、고검출솔급동형반광알산적변연승고솔균고우단순성고혈압조，단순성고혈압조고우건강대조조，차이유통계학의의（P<0.01）。결론대중점인군정기진행혈장동형반광알산、초민C반응단백동태수평적감측，동태평고병정발생발전적엄중정도，제정건강교육대책，이주도조발현、조예방，감소심뇌혈관불량사건적발생，강저뇌졸중적발생여발전。
Objective To investigate the homocysteine (HCY) and Hypersensitive c-reactive protein (hs-CRP) of essential hypertension (EH) patients and hypertensive patients with diabetes and to discuss its corresponding health education. Methods Hypertensive patients were involved into experiment group and health objects into control group. The difference of HCY and hs-CRP was recorded. Results There was positive relationship among HCY, hs-CRP, detection rate, marginal increase of hs-CRP and the high blood pressure. In hypertensive patients with diabetes group, their HCY, hs-CRP and detection rate were higher and there was significant marginal increase of hs-CRP when compared with those in hypertensive patient group. HCY, hs-CRP, detection rate and marginal increase were the lowest in control group. Conclusion Regular detection of HCY and monitoring of hs-CRP of key population contribute to observing the development of hypertension and corresponding health education helps to decrease the incidence of stroke.