CAJ | 학술논문

目的：评价血清降钙素原（PCT）结合急性生理与慢性健康（APACHE Ⅱ）评分在重症监护病房（ICU）老年重症感染患者中病情预测的价值。方法回顾性分析承德市中心医院 ICU 249例患者临床资料，根据临床表现、实验室检查，分为感染组131例，其中脓毒症48例，重度脓毒症43例，脓毒性休克40例；非感染组118例。比较两组 PCT 水平和 APACHE Ⅱ评分结果。结果感染组 PCT 水平显著高于非感染组，差异有统计学意义（P ＜0．01）；感染组中，PCT 水平及 APACHE Ⅱ评分均随病情加重而增高，差异有统计学意义（P ＜0．05）。PCT 与 APACHE Ⅱ评分显著相关（P ＜0．05）。结论 PCT 结合APACHE Ⅱ评分在指导 ICU 老年重症感染患者病情预测方面有重要临床参考价值。
목적：평개혈청강개소원（PCT）결합급성생리여만성건강（APACHE Ⅱ）평분재중증감호병방（ICU）노년중증감염환자중병정예측적개치。방법회고성분석승덕시중심의원 ICU 249례환자림상자료，근거림상표현、실험실검사，분위감염조131례，기중농독증48례，중도농독증43례，농독성휴극40례；비감염조118례。비교량조 PCT 수평화 APACHE Ⅱ평분결과。결과감염조 PCT 수평현저고우비감염조，차이유통계학의의（P ＜0．01）；감염조중，PCT 수평급 APACHE Ⅱ평분균수병정가중이증고，차이유통계학의의（P ＜0．05）。PCT 여 APACHE Ⅱ평분현저상관（P ＜0．05）。결론 PCT 결합APACHE Ⅱ평분재지도 ICU 노년중증감염환자병정예측방면유중요림상삼고개치。
Objective To evaluate the early diagnostic and prognostic implication of procalcitonin (PCT) combined with APACHE Ⅱ score in elderly patients with severe infection in intensive care unit (ICU).Methods The clinical data of 249 patients in ICU of Chengde Central Hospital were retrospectively analyzed.According to the clinical manifestations,laboratory examination,microbiology tests,249 patients were divided into infection group (131 cases)and non-infection group (118 cases).The patients in the infection group were stratified into 3 strata based on severity of infection,specifically:sepsis (48 cases),severe sepsis (43 cases),and septic shock (40 cases).PCT and APACHE Ⅱ score were compared between groups and strata.Results The PCT level of infection group was significantly higher than that of non-infection group (P <0.01).In the infection group,higher PCT level and APACHE Ⅱ score were significantly associated with worse conditions of patients (P <0.05).PCT level was also significantly correlated with APACHE Ⅱ score (P <0.05).Conclusions PCT level is important in early diagnosis of severe infection of elderly patients in ICU.PCT combined with APACHE Ⅱ score may provide important value in assessing the severity of infection for the elderly patients in ICU.