中国眼耳鼻喉科杂志
中國眼耳鼻喉科雜誌
중국안이비후과잡지
CHINESE JOURNAL OF OPHTHALMOLOGY AND OTOLARYNGOLOGY
2015年
1期
32-35
,共4页
白内障%糖尿病视网膜病变%黄斑水肿%超声乳化术%曲安奈德%玻璃体腔注射术
白內障%糖尿病視網膜病變%黃斑水腫%超聲乳化術%麯安奈德%玻璃體腔註射術
백내장%당뇨병시망막병변%황반수종%초성유화술%곡안내덕%파리체강주사술
Cataract%Diabetic retinopathy%Macular edema%Phacoemulsification%Triamcinolone acetonide%Intravitreous injection
目的：评价白内障超声乳化吸除及人工晶状体植入术中玻璃体腔内注射曲安奈德（ TA）对伴有糖尿病黄斑水肿的白内障患者的疗效及安全性。方法25例合并糖尿病黄斑水肿的白内障患者随机分为注药组、对照组，均采用标准的超声乳化白内障吸除及人工晶状体植入术。注药组13例患者术毕时，玻璃体腔内注射TA 4 mg／0．1 mL；对照组12例患者未进行玻璃体药物注射治疗。术后随访1～3个月，观察手术前、后（45±10）d的视力、黄斑中心凹视网膜厚度、眼压及并发症。结果所有患者术后视力较术前皆有提高，但仅有注药组视力改善与术前差异有统计学意义（P＜0．05）。注药组术后视力优于对照组，差异有统计学意义（P＜0．05）。术前和术后（45±10）d黄斑中心厚度：注药组术前比术后明显下降，差异有统计学意义（P＜0．05）。注药组术后黄斑厚度明显低于对照组，差异有统计学意义（ P＜0．05）。对照组术后比术前视网膜厚度有所增加，差异无统计学意义（P＞0．05）。2组间眼压差异无统计学意义（P＞0．05）；2组皆未观察到严重术后并发症。结论白内障超声乳化及人工晶体植入术中联合TA玻璃体腔注射术能够明显提高患者视力，减轻黄斑水肿，为后续观察和治疗创造条件。（中国眼耳鼻喉科杂志，2015，15：32-35）
目的：評價白內障超聲乳化吸除及人工晶狀體植入術中玻璃體腔內註射麯安奈德（ TA）對伴有糖尿病黃斑水腫的白內障患者的療效及安全性。方法25例閤併糖尿病黃斑水腫的白內障患者隨機分為註藥組、對照組，均採用標準的超聲乳化白內障吸除及人工晶狀體植入術。註藥組13例患者術畢時，玻璃體腔內註射TA 4 mg／0．1 mL；對照組12例患者未進行玻璃體藥物註射治療。術後隨訪1～3箇月，觀察手術前、後（45±10）d的視力、黃斑中心凹視網膜厚度、眼壓及併髮癥。結果所有患者術後視力較術前皆有提高，但僅有註藥組視力改善與術前差異有統計學意義（P＜0．05）。註藥組術後視力優于對照組，差異有統計學意義（P＜0．05）。術前和術後（45±10）d黃斑中心厚度：註藥組術前比術後明顯下降，差異有統計學意義（P＜0．05）。註藥組術後黃斑厚度明顯低于對照組，差異有統計學意義（ P＜0．05）。對照組術後比術前視網膜厚度有所增加，差異無統計學意義（P＞0．05）。2組間眼壓差異無統計學意義（P＞0．05）；2組皆未觀察到嚴重術後併髮癥。結論白內障超聲乳化及人工晶體植入術中聯閤TA玻璃體腔註射術能夠明顯提高患者視力，減輕黃斑水腫，為後續觀察和治療創造條件。（中國眼耳鼻喉科雜誌，2015，15：32-35）
목적：평개백내장초성유화흡제급인공정상체식입술중파리체강내주사곡안내덕（ TA）대반유당뇨병황반수종적백내장환자적료효급안전성。방법25례합병당뇨병황반수종적백내장환자수궤분위주약조、대조조，균채용표준적초성유화백내장흡제급인공정상체식입술。주약조13례환자술필시，파리체강내주사TA 4 mg／0．1 mL；대조조12례환자미진행파리체약물주사치료。술후수방1～3개월，관찰수술전、후（45±10）d적시력、황반중심요시망막후도、안압급병발증。결과소유환자술후시력교술전개유제고，단부유주약조시력개선여술전차이유통계학의의（P＜0．05）。주약조술후시력우우대조조，차이유통계학의의（P＜0．05）。술전화술후（45±10）d황반중심후도：주약조술전비술후명현하강，차이유통계학의의（P＜0．05）。주약조술후황반후도명현저우대조조，차이유통계학의의（ P＜0．05）。대조조술후비술전시망막후도유소증가，차이무통계학의의（P＞0．05）。2조간안압차이무통계학의의（P＞0．05）；2조개미관찰도엄중술후병발증。결론백내장초성유화급인공정체식입술중연합TA파리체강주사술능구명현제고환자시력，감경황반수종，위후속관찰화치료창조조건。（중국안이비후과잡지，2015，15：32-35）
Objective To evaluate the effect of intravitreous injection with triamcinolone acetonide ( TA ) for cataract operation with diabetic macular edema .Methods Twenty-five patients performed cataract operation with diabetic macular edema were divided into two groups .The injection group ( 13 patients ) was performed intravitreous injection with TA,the control group (12 patients ) was not performed intravitreous injection .The visual acuity, retinal thickness of central fovea of macula and intraocular pressure before and after the operation (45 ±10 d) were observed. Results All the patients had better the visual acuity after surgery than before the surgery , however , there was statistically significant difference of visual acuity improvement only in injection group (P<0.05).The postoperative visual acuity of the injection group was better than that of the control group , and there was statistically significant difference between the two groups (P<0.05).Besides, there was statistically significant difference of central macular thickness between preoperative and (45 ±10) d postoperative (P <0.05).There was no significant difference of intraocular pressure between the two groups (P >0.05).Conclusions Intravitreous injection with triamcinolone acetonide for phacoemulsification can significantly improve visual acuity , alleviate macular edema , and provide better prognosis for follow-up and treatment .
