CAJ | 학술논문

目的：探讨儿童A型流感病毒肺炎与呼吸道合胞病毒性肺炎中血清可溶性细胞间黏附分子-1的表达及其意义，以指导临床治疗和预防。方法：选取于本科住院的肺炎儿童，根据逆转录聚合酶链反应结果分为FA组（A型流感病毒阳性）36例，RSV组（呼吸道合胞病毒阳性）22例，同时选取同期来本院体检的健康儿童41例为对照组，分析比较三组儿童的血清sICAM-1值。结果：FA组和RSV组血清sICAM-1值均高于对照组，比较差异有统计学意义（P<0.05）。结论：A型流感病毒肺炎与呼吸道合胞病毒性肺炎儿童中sICAM-1表达水平升高，是导致儿童气道炎症的重要炎症因子之一，可为临床治疗采用抗粘附疗法及抗炎抑制炎性因子提供佐证。
목적：탐토인동A형류감병독폐염여호흡도합포병독성폐염중혈청가용성세포간점부분자-1적표체급기의의，이지도림상치료화예방。방법：선취우본과주원적폐염인동，근거역전록취합매련반응결과분위FA조（A형류감병독양성）36례，RSV조（호흡도합포병독양성）22례，동시선취동기래본원체검적건강인동41례위대조조，분석비교삼조인동적혈청sICAM-1치。결과：FA조화RSV조혈청sICAM-1치균고우대조조，비교차이유통계학의의（P<0.05）。결론：A형류감병독폐염여호흡도합포병독성폐염인동중sICAM-1표체수평승고，시도치인동기도염증적중요염증인자지일，가위림상치료채용항점부요법급항염억제염성인자제공좌증。
Objective: The expression and significance of serum soluble intercellular adhesion molecule-1 in children with influenza A virus pneumonia and respiratory syncytial virus pneumonia in -1, in order to guide the clinical treatment and prevention.Method: In our hospital from pneumonia in children, according to the reverse transcriptase polymerase chain reaction results were divided into FA group (A influenza virus positive) 36 cases, group RSV (respiratory syncytial virus positive) in 22 cases, at the same time in healthy children at our hospital physical examination 41 cases as control group, serum sICAM-1 were compared between the three groups children’s value.Result: In FA group and RSV group, serum sICAM-1 values were higher than those in the control group, there was significant difference (P<0.05). Conclusion: The expression of A increased the level of sICAM-1 influenza virus pneumonia and respiratory syncytial virus pneumonia in children, which is one of the important inflammatory airway inflammation in children, can provide clinical treatment with anti adhesion therapy and anti-inflammatory, inhibiting inflammatory factors to provide evidence.