CAJ | 학술논문

目的：探讨支气管扩张患者长期应用小剂量罗红霉素联合氨茶碱的疗效。方法：选取2012年3月-2013年3月于本院进行治疗的支气管扩张患者112例，随机数字表法分为对照组和治疗组，每组56例。对照组给予罗红霉素治疗，治疗组在对照组治疗方法的基础上给予氨茶碱治疗。治疗1年后观察两组治疗前后的肺功能指标、痰量、发作次数的变化及其总有效率。结果：治疗组治疗后功能指标、痰量、发作次数优于对照组，比较差异具有统计学意义（P<0.05）。治疗组的总有效率（94.6%）与对照组（75.0%）比较，差异具有统计学意义（P<0.05）。结论：小剂量罗红霉素联合氨茶碱治疗支气管扩张疗效确切，值得在临床上推广使用。
목적：탐토지기관확장환자장기응용소제량라홍매소연합안다감적료효。방법：선취2012년3월-2013년3월우본원진행치료적지기관확장환자112례，수궤수자표법분위대조조화치료조，매조56례。대조조급여라홍매소치료，치료조재대조조치료방법적기출상급여안다감치료。치료1년후관찰량조치료전후적폐공능지표、담량、발작차수적변화급기총유효솔。결과：치료조치료후공능지표、담량、발작차수우우대조조，비교차이구유통계학의의（P<0.05）。치료조적총유효솔（94.6%）여대조조（75.0%）비교，차이구유통계학의의（P<0.05）。결론：소제량라홍매소연합안다감치료지기관확장료효학절，치득재림상상추엄사용。
Objective: To investigate efficacy of long-term and low-dose Luo erythromycin combined with aminophylline in treatment of patients with bronchiectasis.Method: From March 2012 to March 2013 in our hospital 112 patients with bronchiectasis were randomly divided into control group and observation group,each contained 56 cases. The control group was treated by Luo erythromycin. On the basis of the control group,observation group was treated by aminophylline, additionally. Lung function, sputum volume, attack times, effectiveness were observed before and after 1 year of treatment.Result: Lung function, sputum volume, attack times of observation group were better than those of the control group after 1 year of treatment, with a statistically significant difference (P<0.05). The total efficiency of the observation group (95.4%) was better than that of the control group (76.4%), with a statistically significant difference (P<0.05).Conclusion: Long-term and low-dose Luo erythromycin combined with aminophylline in treatment of patients with bronchiectasis showed sastifying efficacy and worthy of introduction.