中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
34期
130-132
,共3页
围手术期%预防用抗菌药物%合理性%评价指标体系
圍手術期%預防用抗菌藥物%閤理性%評價指標體繫
위수술기%예방용항균약물%합이성%평개지표체계
Perioperation period%Prophylactic antibiotics%Rationality%Evaluation index system
目的：建立围手术期预防用抗菌药物合理性评价指标体系，促进围手术期预防用抗菌药物使用的合理性。方法：于本院病历检索系统中随机抽取250例围手术期预防用抗菌药物病例，设计围手术期预防用抗菌药物调查表。搜集有关围手术期预防用抗菌药物合理性评价体系研究的相关资料，以国家颁布的有关抗菌药物合理性评价的指南和规定为指导，采用Delphi Method法建立围手术期预防用抗菌药物合理性评价指标体系。并运用该评价指标体系对本组患者用药的合理性进行综合评价。结果：本研究建立了一个由3个一级指标和13个二级指标组成的评价体系。该指标体系对本组患者围术期预防用药的评价结果为：有用药指征患者共202例（80.8%），无用药指征患者共48例（19.2%）；用药方案不合理患者占总体患者的比率依次为：药物选择12.8%、给药途径4.8%、溶媒选择5.2%、溶媒用量10%、用药频次20.8%、用药剂量22%。同时，本组患者围术期使用预防用抗菌药物后，仅2例患者出现轻微手术部位感染，比率为0.8%。结论：Delphi Method法下建立的由3个一级指标和13个二级指标组成的评价体系能系统性的对围手术期预防用抗菌药物使用的合理性进行评价，较客观标准。
目的：建立圍手術期預防用抗菌藥物閤理性評價指標體繫，促進圍手術期預防用抗菌藥物使用的閤理性。方法：于本院病歷檢索繫統中隨機抽取250例圍手術期預防用抗菌藥物病例，設計圍手術期預防用抗菌藥物調查錶。搜集有關圍手術期預防用抗菌藥物閤理性評價體繫研究的相關資料，以國傢頒佈的有關抗菌藥物閤理性評價的指南和規定為指導，採用Delphi Method法建立圍手術期預防用抗菌藥物閤理性評價指標體繫。併運用該評價指標體繫對本組患者用藥的閤理性進行綜閤評價。結果：本研究建立瞭一箇由3箇一級指標和13箇二級指標組成的評價體繫。該指標體繫對本組患者圍術期預防用藥的評價結果為：有用藥指徵患者共202例（80.8%），無用藥指徵患者共48例（19.2%）；用藥方案不閤理患者佔總體患者的比率依次為：藥物選擇12.8%、給藥途徑4.8%、溶媒選擇5.2%、溶媒用量10%、用藥頻次20.8%、用藥劑量22%。同時，本組患者圍術期使用預防用抗菌藥物後，僅2例患者齣現輕微手術部位感染，比率為0.8%。結論：Delphi Method法下建立的由3箇一級指標和13箇二級指標組成的評價體繫能繫統性的對圍手術期預防用抗菌藥物使用的閤理性進行評價，較客觀標準。
목적：건립위수술기예방용항균약물합이성평개지표체계，촉진위수술기예방용항균약물사용적합이성。방법：우본원병력검색계통중수궤추취250례위수술기예방용항균약물병례，설계위수술기예방용항균약물조사표。수집유관위수술기예방용항균약물합이성평개체계연구적상관자료，이국가반포적유관항균약물합이성평개적지남화규정위지도，채용Delphi Method법건립위수술기예방용항균약물합이성평개지표체계。병운용해평개지표체계대본조환자용약적합이성진행종합평개。결과：본연구건립료일개유3개일급지표화13개이급지표조성적평개체계。해지표체계대본조환자위술기예방용약적평개결과위：유용약지정환자공202례（80.8%），무용약지정환자공48례（19.2%）；용약방안불합리환자점총체환자적비솔의차위：약물선택12.8%、급약도경4.8%、용매선택5.2%、용매용량10%、용약빈차20.8%、용약제량22%。동시，본조환자위술기사용예방용항균약물후，부2례환자출현경미수술부위감염，비솔위0.8%。결론：Delphi Method법하건립적유3개일급지표화13개이급지표조성적평개체계능계통성적대위수술기예방용항균약물사용적합이성진행평개，교객관표준。
Objective:To establish rational evaluation index system and to improve the rationality of prophylactic use the antibiotics during perioperation period.Method:250 cases were randomly collected and analyzed by the relevant medical records of antibacterials during perioperation period,then questionnaire about prophylactic used of antibiotics during perioperation period was designed. After that,the relevant data of prophylactic used of antibiotics during perioperation period was collected and the perioperation period of prophylactic antimicrobial evaluation index system of drugs with Delphi Method method was used to analyze and evaluate the rationality of prophylactic use of antibiotics. Result:The result used a evaluation index system consist of three first class indexes and thirteen second class indexes were that there were 202 cases(80.8%)with drug indications in patients while 48 cases(19.2%)without drug indications. Unreasonable medication proportions of total patients as follows:drug selection was 12.8%,administration route was 4.8%,irrational solvent choice was 5.2%,the solvent amount was 10%,the total application frequency of administration was 20.8%,the dose of drug was 22%.At the same time,only two patients had mild operation site infection in this group of patients after using prophylactic antibiotics,of which the utilization ratio was 0.8%. Conclusion:The evaluation index system of prophylactic use of antibiotics during perioperation period,which consists of three first class indexes and thirteen second class indexes using the established Delphi Method method is feasible and rational.
