中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2014年
11期
43-45
,共3页
非洛地平%厄贝沙坦%高血压%勃起功能障碍
非洛地平%阨貝沙坦%高血壓%勃起功能障礙
비락지평%액패사탄%고혈압%발기공능장애
Felodipine%Irbesartan%hypertension%verectile dysfunction
目的：评价非洛地平缓释片联合厄贝沙坦片对男性高血压患者勃起功能的影响。方法选择我院从2012年10月到2013年10月收治的男性高血压患者240例，随机分为两组，每组各120例。对观察组患者采取非洛地平缓释片联合厄贝沙坦片治疗，而对照组患者仅采用非洛地平缓释片治疗。结果两组患者治疗后4周、24周、48周的降压达标率和有效率比较，差异无统计学意义（P＞0.05）。治疗后，观察组患者ED患病率明显下降。治疗后48周，观察组轻度ED患病率显著低于对照组，差异有统计学意义（P＜0.01）。治疗48周后，观察组患者血清睾酮（T）明显升高，而血清性激素结合球蛋白（SHBG）显著下降，与对照组相比差异具有统计学意义（P＜0.01~0.05）。结论非洛地平缓释片联合厄贝沙坦片治疗男性高血压患者可能对患者的性功能影响较小，医疗应用价值显著。
目的：評價非洛地平緩釋片聯閤阨貝沙坦片對男性高血壓患者勃起功能的影響。方法選擇我院從2012年10月到2013年10月收治的男性高血壓患者240例，隨機分為兩組，每組各120例。對觀察組患者採取非洛地平緩釋片聯閤阨貝沙坦片治療，而對照組患者僅採用非洛地平緩釋片治療。結果兩組患者治療後4週、24週、48週的降壓達標率和有效率比較，差異無統計學意義（P＞0.05）。治療後，觀察組患者ED患病率明顯下降。治療後48週，觀察組輕度ED患病率顯著低于對照組，差異有統計學意義（P＜0.01）。治療48週後，觀察組患者血清睪酮（T）明顯升高，而血清性激素結閤毬蛋白（SHBG）顯著下降，與對照組相比差異具有統計學意義（P＜0.01~0.05）。結論非洛地平緩釋片聯閤阨貝沙坦片治療男性高血壓患者可能對患者的性功能影響較小，醫療應用價值顯著。
목적：평개비락지평완석편연합액패사탄편대남성고혈압환자발기공능적영향。방법선택아원종2012년10월도2013년10월수치적남성고혈압환자240례，수궤분위량조，매조각120례。대관찰조환자채취비락지평완석편연합액패사탄편치료，이대조조환자부채용비락지평완석편치료。결과량조환자치료후4주、24주、48주적강압체표솔화유효솔비교，차이무통계학의의（P＞0.05）。치료후，관찰조환자ED환병솔명현하강。치료후48주，관찰조경도ED환병솔현저저우대조조，차이유통계학의의（P＜0.01）。치료48주후，관찰조환자혈청고동（T）명현승고，이혈청성격소결합구단백（SHBG）현저하강，여대조조상비차이구유통계학의의（P＜0.01~0.05）。결론비락지평완석편연합액패사탄편치료남성고혈압환자가능대환자적성공능영향교소，의료응용개치현저。
Objective To study the effects of Felodipine Sustained Release Tablets joint Irbesartan Tablets on erectile function of male patients with hypertension.Methods Total of 240 male patients with hypertension in our hospital, from 2012 October to 2013 October, were randomly divided into two groupssuch as the observation group(120 patientstreated with Felodipine Sustained Release Tablets joint Irbesartan Tablets, and control group(120 patients only treated by Felodipine Sustained Release Tablets.Results In 4th weeks after treatment, 24th weeks after the treatment and 48th weeks after treatment,there were no significant differences in blood pressure control rate and efficiency comparison between the two groups (P>0.05). After treatment, the prevalence of ED in the observation group decreased significantly. After 48 weeks of treatment,mild ED prevalence of the observation group was significantly less than that of the control group (P<0.01). After 48 weeks treatment, the levels of serum T of the patients in the observation group were increased but the levels of serum SHBG of the patients in observation group were decreased. Compared with that of the control group, the difference was statistically significant (P<0.01-0.05).Conclusion Felodipine Sustained Release Tablets joint Irbesartan Tablets may be more effective in the treatment of sexual function of patients with hypertension,and show better clinical application.
