中国男科学杂志
中國男科學雜誌
중국남과학잡지
CHINESE JOURNAL OF ANDROLOGY
2014年
11期
40-42,47
,共4页
前列腺肿瘤%下尿路梗阻%激光疗法
前列腺腫瘤%下尿路梗阻%激光療法
전렬선종류%하뇨로경조%격광요법
prostatic neoplasms%lower urinary tract obstruction%laser therapy
目的：探讨2μm激光汽化术治疗晚期前列腺癌下尿路梗阻疗效。方法从2012年2月至2013年9月，我院采用2μm激光汽化术治疗晚期前列腺癌下尿路梗阻患者26例，术前评估准备、观察平均手术时间、血浆血红蛋白降低，术前、后国际前列腺症状评分（IPSS）、生活质量评分（QoL）、残余尿量（RUV）及最大尿流率（Qmax）变化等指标。结果26例患者手术成功，手术病人无输血，没有患者出现前列腺电切综合征。平均手术时间为（81.2±24.4）min，平均血红蛋白下降（6.4±3.2）g/L。术前PSA，IPSS，QoL，Qmax，RUV分别为（13.9±4.2）μg/mL,（23.6±4.1），（5.9±1.2），（7.3±2.3）mL/s，（147.3±55.4）mL。术后1个月随访 PSA，IPSS， QoL，Qmax，RUV变化，分别为（1.6±0.8）μg/mL，（8.8±2.9），（2.4±0.8），（15.8±3.6）mL/s，（40.6±19.3） mL。手术前后各项指标差异均有统计学意义（P＜0.01）。结论2μm激光汽化术针对治疗晚期前列腺癌下尿路梗阻是安全有效的微创手术方式。
目的：探討2μm激光汽化術治療晚期前列腺癌下尿路梗阻療效。方法從2012年2月至2013年9月，我院採用2μm激光汽化術治療晚期前列腺癌下尿路梗阻患者26例，術前評估準備、觀察平均手術時間、血漿血紅蛋白降低，術前、後國際前列腺癥狀評分（IPSS）、生活質量評分（QoL）、殘餘尿量（RUV）及最大尿流率（Qmax）變化等指標。結果26例患者手術成功，手術病人無輸血，沒有患者齣現前列腺電切綜閤徵。平均手術時間為（81.2±24.4）min，平均血紅蛋白下降（6.4±3.2）g/L。術前PSA，IPSS，QoL，Qmax，RUV分彆為（13.9±4.2）μg/mL,（23.6±4.1），（5.9±1.2），（7.3±2.3）mL/s，（147.3±55.4）mL。術後1箇月隨訪 PSA，IPSS， QoL，Qmax，RUV變化，分彆為（1.6±0.8）μg/mL，（8.8±2.9），（2.4±0.8），（15.8±3.6）mL/s，（40.6±19.3） mL。手術前後各項指標差異均有統計學意義（P＜0.01）。結論2μm激光汽化術針對治療晚期前列腺癌下尿路梗阻是安全有效的微創手術方式。
목적：탐토2μm격광기화술치료만기전렬선암하뇨로경조료효。방법종2012년2월지2013년9월，아원채용2μm격광기화술치료만기전렬선암하뇨로경조환자26례，술전평고준비、관찰평균수술시간、혈장혈홍단백강저，술전、후국제전렬선증상평분（IPSS）、생활질량평분（QoL）、잔여뇨량（RUV）급최대뇨류솔（Qmax）변화등지표。결과26례환자수술성공，수술병인무수혈，몰유환자출현전렬선전절종합정。평균수술시간위（81.2±24.4）min，평균혈홍단백하강（6.4±3.2）g/L。술전PSA，IPSS，QoL，Qmax，RUV분별위（13.9±4.2）μg/mL,（23.6±4.1），（5.9±1.2），（7.3±2.3）mL/s，（147.3±55.4）mL。술후1개월수방 PSA，IPSS， QoL，Qmax，RUV변화，분별위（1.6±0.8）μg/mL，（8.8±2.9），（2.4±0.8），（15.8±3.6）mL/s，（40.6±19.3） mL。수술전후각항지표차이균유통계학의의（P＜0.01）。결론2μm격광기화술침대치료만기전렬선암하뇨로경조시안전유효적미창수술방식。
Objective To explore the efficacy and safety of two micron continuous wave laser in the treatment of lower urinary tract obstruction caused by advanced prostate cancer.Methods Clinical data of 26 patients with lower urinary tract obstruction caused by advanced prostate cancer, who underwent two micron continuous wave laser, were analyzed retrospectively. The operative time, Hemoglobin decrease and operative complications was recorded. The variables such as PSA, IPSS, QoL, Qmax, post-void residual urine volume(RUV)were measured and analyzed before and after operations.Results All operations were performed successfully. None of patients received blood transfusion or had TURP syndrome. The mean operative time was 81.2±24.4 min, and the mean hemoglobin decrease was 6.4±3.2 g/L. The pre-operative levels of PSA, IPSS, QoL, Qmax, RUV were 13.9±4.2μg/mL, 23.6±4.1, 5.9±1.2, 7.3±2.3 mL/s and 147.3± 55.4 mL,respectively, and postoperative levels of PSA, IPSS, QoL, Qmax and RUV were 1.6±0.8μg/mL, 8.8±2.9, 2.4±0.8, 15.8±3.6 and 40.6±19.3. There were significant differences in above parameters between before operation and after operation(P<0.01). Few complications were found and good outcomes of operation was for all treated patients. Conclusion The two micron continuous wave laser may be a safe, efficient and minimal invasive treatment therapeutic option for lower urinary tract obstruction caused by advanced prostate cancer.
