中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
3期
69-71
,共3页
TORCH(IgM%IgG)%孕期筛查%不良妊娠结局
TORCH(IgM%IgG)%孕期篩查%不良妊娠結跼
TORCH(IgM%IgG)%잉기사사%불량임신결국
TORCH(IgM、IgG)%Screening during pregnancy%Adverse pregnancy outcomes
目的：了解朝阳地区孕妇的TORCH感染情况，及随访TORCH-IgM抗体阳性孕妇的不良妊娠结局，为提高孕妇保健工作提供实验数据。方法：对就诊的2365例孕妇采集血清，采用捕获法ELISA原理检测TORCH-IgM抗体，用ELISA间接法原理检测TORCH-IgG抗体。结果：2365例早孕妇进行TORCH特异性抗体IgM和IgG检测，筛查出5种病原体特异性IgM抗体阳性孕妇共25例，总阳性率为1.05%。从感染的情况看，CMV（0.34%）>HSV（0.25%）>RV（0.25%）>TOX（0.16%），CMV感染率最高，其次为HSV、RV。CMV、HSVⅠ、RV特异性抗体IgG在妊娠状态下均有较高的检出率，分别为：89.85%、89.89%、81.48%。25例TORCH感染孕妇中不良妊娠结局14例，流产发生率最高为47.26%（10/21），另外11例在孕期均抽取羊水细胞培养，诊断出3例异常核型。结论：对育龄妇女进行TORCH（IgM、IgG）孕前筛查可有效的减少异常患儿的出生，TORCH检测在孕期筛查中有重要意义。
目的：瞭解朝暘地區孕婦的TORCH感染情況，及隨訪TORCH-IgM抗體暘性孕婦的不良妊娠結跼，為提高孕婦保健工作提供實驗數據。方法：對就診的2365例孕婦採集血清，採用捕穫法ELISA原理檢測TORCH-IgM抗體，用ELISA間接法原理檢測TORCH-IgG抗體。結果：2365例早孕婦進行TORCH特異性抗體IgM和IgG檢測，篩查齣5種病原體特異性IgM抗體暘性孕婦共25例，總暘性率為1.05%。從感染的情況看，CMV（0.34%）>HSV（0.25%）>RV（0.25%）>TOX（0.16%），CMV感染率最高，其次為HSV、RV。CMV、HSVⅠ、RV特異性抗體IgG在妊娠狀態下均有較高的檢齣率，分彆為：89.85%、89.89%、81.48%。25例TORCH感染孕婦中不良妊娠結跼14例，流產髮生率最高為47.26%（10/21），另外11例在孕期均抽取羊水細胞培養，診斷齣3例異常覈型。結論：對育齡婦女進行TORCH（IgM、IgG）孕前篩查可有效的減少異常患兒的齣生，TORCH檢測在孕期篩查中有重要意義。
목적：료해조양지구잉부적TORCH감염정황，급수방TORCH-IgM항체양성잉부적불량임신결국，위제고잉부보건공작제공실험수거。방법：대취진적2365례잉부채집혈청，채용포획법ELISA원리검측TORCH-IgM항체，용ELISA간접법원리검측TORCH-IgG항체。결과：2365례조잉부진행TORCH특이성항체IgM화IgG검측，사사출5충병원체특이성IgM항체양성잉부공25례，총양성솔위1.05%。종감염적정황간，CMV（0.34%）>HSV（0.25%）>RV（0.25%）>TOX（0.16%），CMV감염솔최고，기차위HSV、RV。CMV、HSVⅠ、RV특이성항체IgG재임신상태하균유교고적검출솔，분별위：89.85%、89.89%、81.48%。25례TORCH감염잉부중불량임신결국14례，유산발생솔최고위47.26%（10/21），령외11례재잉기균추취양수세포배양，진단출3례이상핵형。결론：대육령부녀진행TORCH（IgM、IgG）잉전사사가유효적감소이상환인적출생，TORCH검측재잉기사사중유중요의의。
Objective: To investigate the infection of pregnant women in Chaoyang area TORCH, and follow-up of TORCH-IgM antibody positive pregnant women with adverse pregnancy outcomes, in order to improve the health care of pregnant women and provide experimental data.Method: 2365 cases of pregnant women serum on treatment of acquisition, detection of TORCH-IgM antibody by capture ELISA method for TORCH-IgG antibody detection principle, the principle of indirect ELISA method.Result:2365 cases of early pregnant women were TORCH specific antibody detection of IgM and IgG positive pregnant women, screening of specific IgM antibody of five kinds of pathogens in 25 cases, the total positive rate was 1.05%. From the infection situation,CMV(0.34%),HSV(0.25%)>RV(0.25%)>TOX(0.16%),CMV infection rate was the highest, followed by HSV, RV. CMV, HSV I, RV specific antibody IgG in pregnancy condition had a higher detection rate, respectively: 89.85%, 89.89%, 81.48%. In 14 cases of pregnant women with adverse pregnancy outcome of 25 cases of TORCH infection, the highest incidence of abortion. The other 11 cases were sampled during pregnancy amniotic fluid cell culture, diagnosed 3 cases of abnormal karyotype.Conclusion: TORCH is performed in women of childbearing age (IgM, IgG) screening before pregnancy can effectively reduce the abnormal infants birth, TORCH detection is of important significance in prenatal screening.
