CAJ | 학술논문

目的：探究肺癌放疗后复发适形放疗的疗效。方法选取72例肺癌复发患者，应用随机数字表法进行分组，分别为研究组和对照组，每组各36例。其中对照组实施常规放疗联合化疗，研究组则采用适形放疗联合化疗。两组放射剂量均控制在60～70 Gy，1次／d，5次／w，7w为1个疗程。化疗药物选取紫杉醇联合顺铂，1次／w，7w为1个疗程。结果研究组近期癌肿缓解率为83．3％，对照组为50．0％，差异有统计学意义（P＜0．05）。研究组1年及2年生存率分别为66．7％和52．8％，对照组分别为52．8％和33．3％，差异有统计学意义（ P＜0．05）。研究组放疗不良反应发生率为8．3％，对照组为11．1％，差异有统计学意义（P＞0．05）。结论三维适形放疗技术联合化疗药物相较于传统放化疗，更能有效提高复发性肺癌患者的生存率，且不良反应能有效控制。
목적：탐구폐암방료후복발괄형방료적료효。방법선취72례폐암복발환자，응용수궤수자표법진행분조，분별위연구조화대조조，매조각36례。기중대조조실시상규방료연합화료，연구조칙채용괄형방료연합화료。량조방사제량균공제재60～70 Gy，1차／d，5차／w，7w위1개료정。화료약물선취자삼순연합순박，1차／w，7w위1개료정。결과연구조근기암종완해솔위83．3％，대조조위50．0％，차이유통계학의의（P＜0．05）。연구조1년급2년생존솔분별위66．7％화52．8％，대조조분별위52．8％화33．3％，차이유통계학의의（ P＜0．05）。연구조방료불량반응발생솔위8．3％，대조조위11．1％，차이유통계학의의（P＞0．05）。결론삼유괄형방료기술연합화료약물상교우전통방화료，경능유효제고복발성폐암환자적생존솔，차불량반응능유효공제。
Objective To explore the effects of conformal radiotherapy for recurrent lung cancer after radiotherapy. Methods 72 cases of recurrent lung cancer patients were divided into the study group and the control group using the random number table,each group had 36 cases.The control group received routine radiotherapy combined with chemotherapy,the study group received conformal radiotherapy combined with chemotherapy.Two groups of radiation dose was controlled under 60 ~70 Gy,1 /d,5 /w,7 weeks for a course of treatment.Results Recent tumor remission rates of the study group and the control group were 83.3%and 50.00%,the difference was statistically significant(P<0.05).The 1-and 2-year survival rates of the study group were 66.7% and 52.8%,the control group were 52.8% and 33.3%,the difference was statistically significant(P<0.05).The incidence of adverse events of the study group was 8.3%,and 11.1%in the control group,the difference was statisti-cally significant(P>0.05).Conclusion Three dimensional conformal radiotherapy combined with chemotherapy compared with radiotherapy and chemotherapy,can improve the survival rate of patients with recurrent lung cancer,and effectively control the tox-icities.