CAJ | 학술논문

目的：探讨Ⅰ、Ⅱ期卵巢交界性肿瘤（ BOTs）的治疗方法及影响复发和预后的因素。方法回顾性分析93例Ⅰ、Ⅱ期BOTs患者的临床资料。结果Ⅰ期BOTs患者87例（93．5％），Ⅱ期6例（6．5％）。病理类型以浆液性39例（41．9％）和黏液性肿瘤46例（49．5％）为主。所有患者均行手术治疗，38例（40．9％）行保守性手术，55例（59．1％）行根治性手术。93例中24例行术后辅助化疗，Ⅰ期22例，Ⅱ期2例。93例中5例复发，复发率为5．4％，均为Ⅰ期行保守性手术且术后未行化疗的患者，平均复发时间为39．8个月（12～72个月），中位复发时间为36个月，无1例死亡。结论Ⅰ、Ⅱ期BOTs预后良好，手术是其主要的治疗手段，保守性手术治疗虽然会影响复发率，但不影响生存期；对有高危因素患者，术后短期内给予化疗，可减少复发，但不能改变患者预后。
목적：탐토Ⅰ、Ⅱ기란소교계성종류（ BOTs）적치료방법급영향복발화예후적인소。방법회고성분석93례Ⅰ、Ⅱ기BOTs환자적림상자료。결과Ⅰ기BOTs환자87례（93．5％），Ⅱ기6례（6．5％）。병리류형이장액성39례（41．9％）화점액성종류46례（49．5％）위주。소유환자균행수술치료，38례（40．9％）행보수성수술，55례（59．1％）행근치성수술。93례중24례행술후보조화료，Ⅰ기22례，Ⅱ기2례。93례중5례복발，복발솔위5．4％，균위Ⅰ기행보수성수술차술후미행화료적환자，평균복발시간위39．8개월（12～72개월），중위복발시간위36개월，무1례사망。결론Ⅰ、Ⅱ기BOTs예후량호，수술시기주요적치료수단，보수성수술치료수연회영향복발솔，단불영향생존기；대유고위인소환자，술후단기내급여화료，가감소복발，단불능개변환자예후。
Objective To investigate the treatment forⅠandⅡborderline ovarian tumors ( BOTs) and influence fac-tors of recurrence and prognosis.Methods Clinical data of 93 cases ofⅠandⅡBOTs were retrospectively analyzed.Results 87 cases (93.5%) were stageⅠBOTs,6 cases (6.5%) were stageⅡBOTs.The pathological types were mainly serous 39 cases (41.9%)and mucinous tumors 46 cases (49.5%).Patients all underwent surgery,38 cases received conservative surgery (40.9%),55 cases(59.1%) received radical surgery.Among the 93 cases,24 cases received postoperative adjuvant chemother-apy,stageⅠwas 22 cases,stageⅡwas 2 cases.Among the 93 patients,there had 5 cases of recurrence,the recurrence rate was 5.4%,these patients were stageⅠtreated with conservative surgery without postoperative chemotherapy,average recurrence time was 39.8 months (12~72 months),median time to recurrence was 36 months,with no deaths.Conclusion Stage Ⅰ and ⅡBOTs has good prognosis,and operation is the main treatment method,although conservative surgery affects the recurrence rate, but does not affect survival;patients with high risk factors should receive chemotherapy shortly after surgery,it can reduce the re-currence,but can not change the prognosis of patients.