CAJ | 학술논문

目的：比较与分析开腹与腹腔镜手术治疗子宫内膜癌患者的临床效果。方法选取66例子宫内膜癌患者作为研究对象，按照随机数字表法分为对照组和治疗组。对照组采用传统开腹手术治疗；治疗组采用腹腔镜手术治疗。比较两组患者术前、术后4 d CD4／CD8水平和IgG表达情况。同时观察两组患者术中出血量和手术时间及肛门排气时间、术后自主下床活动时间等。结果治疗后治疗组患者术中出血量和手术时间及肛门排气时间、术后自主下床活动时间、留置尿管时间、平均住院时间分别为（120．24±6．17）ml、（64．19±9．47）min、（0．67±0．18）d、（3．19±0．71）d、（0．61±0．17）d、（12．47±2．41）d；对照组分别为（347．96±11．75）ml、（98．71±10．15）min、（1．69±0．47）d、（6．27±0．82）d、（2．12±0．31）d、（18．36±3．15）d，两组比较有显著性差异（P＜0．05）。治疗组患者术后发热发生率和并发症发生率分别为6．06％、6．06％，明显低于对照组的18．18％、18．18％（χ2＝3．75，7．88，P均＜0．05）。术后4 d，治疗组患者4 d CD4／CD8水平和IgG表达水平与对照组比较有显著性差异（ P＜0．05）。结论与传统开腹手术比较，采用腹腔镜手术治疗子宫内膜癌患者，患者创伤小，同时对患者体液免疫和细胞免疫功能影响较小，对患者术后恢复有一定帮助。
목적：비교여분석개복여복강경수술치료자궁내막암환자적림상효과。방법선취66례자궁내막암환자작위연구대상，안조수궤수자표법분위대조조화치료조。대조조채용전통개복수술치료；치료조채용복강경수술치료。비교량조환자술전、술후4 d CD4／CD8수평화IgG표체정황。동시관찰량조환자술중출혈량화수술시간급항문배기시간、술후자주하상활동시간등。결과치료후치료조환자술중출혈량화수술시간급항문배기시간、술후자주하상활동시간、류치뇨관시간、평균주원시간분별위（120．24±6．17）ml、（64．19±9．47）min、（0．67±0．18）d、（3．19±0．71）d、（0．61±0．17）d、（12．47±2．41）d；대조조분별위（347．96±11．75）ml、（98．71±10．15）min、（1．69±0．47）d、（6．27±0．82）d、（2．12±0．31）d、（18．36±3．15）d，량조비교유현저성차이（P＜0．05）。치료조환자술후발열발생솔화병발증발생솔분별위6．06％、6．06％，명현저우대조조적18．18％、18．18％（χ2＝3．75，7．88，P균＜0．05）。술후4 d，치료조환자4 d CD4／CD8수평화IgG표체수평여대조조비교유현저성차이（ P＜0．05）。결론여전통개복수술비교，채용복강경수술치료자궁내막암환자，환자창상소，동시대환자체액면역화세포면역공능영향교소，대환자술후회복유일정방조。
Objective To compare and analyze the clinical efficacy of open and laparoscopic surgery for endometrial car-cinoma.Methods 66 endometrial carcinoma patients were selected as the research object.And according to random number ta-ble method were grouped into the control group and the treatment group.The control group received the traditional laparotomy sur-gery;The treatment group received the laparoscopic surgery.Preoperative and postoperative 4 d CD4/CD8 levels and IgG expres-sion of the 2 groups were observed and compared.Intraoperative blood loss,operation time,the anus exhaust time,postoperative autonomous bed activity time of the 2 groups were observed.Results After treatment,blood loss,operative time,anal exhaust time,after independent ambulation,indwelling catheter time,and the average length of hospital stay were(120.24 ±6.17) ml, (64.19 ±9.47) min,(0.67 ±0.18) d,(3.19 ±0.71) d,(0.61 ±0.17) d,(12.47 ±2.41) d;the control group were(347.96 ±11.75) ml,(98.71 ±10.15) min,(1.69 ±0.47 ) d,(6.27 ±0.82) d,(2.12 ±0.31) d,(18.36 ±3.15) d,there was significant difference( P<0.05) between the 2 groups.Postoperative fever incidence and complication rates of the treatment group were 6.06%,6.06%,significantly lower than 18.18%,18.18%(χ2 =3.75,7.88,P<0.05) in the control group.Postoperative 4 d,there was a significant difference(P<0.05) in 4 d CD4/CD8 expression levels and IgG levels between the 2 groups.Conclu-sion Compared with traditional open surgery,laparoscopic surgery for endometrial cancer has small effect on humoral and cellu-lar immune function,with small trauma,it is of some help on postoperative recovery.