CAJ | 학술논문

目的：探讨紫杉醇联合卡铂化疗治疗卵巢癌的效果。方法收集92例卵巢癌患者的临床资料，根据不同的治疗方法，将患者分为对照组与观察组，每组各46例。对照组患者单纯采取卡铂化疗，观察组患者采取紫杉醇联合卡铂化疗。分析2组患者临床疗效与不良反应发生率。结果观察组治疗总有效率为89．13％，对照组总有效率为63．04％，差异有统计学意义（P＜0．05）。观察组不良反应发生率为26．09％，对照组为23．91％，差异无统计学意义（P＞0．05）。结论紫杉醇联合卡铂治疗晚期卵巢癌的临床效果明显优于单纯卡铂治疗，患者均可耐受出现的不良反应，值得临床推广。
목적：탐토자삼순연합잡박화료치료란소암적효과。방법수집92례란소암환자적림상자료，근거불동적치료방법，장환자분위대조조여관찰조，매조각46례。대조조환자단순채취잡박화료，관찰조환자채취자삼순연합잡박화료。분석2조환자림상료효여불량반응발생솔。결과관찰조치료총유효솔위89．13％，대조조총유효솔위63．04％，차이유통계학의의（P＜0．05）。관찰조불량반응발생솔위26．09％，대조조위23．91％，차이무통계학의의（P＞0．05）。결론자삼순연합잡박치료만기란소암적림상효과명현우우단순잡박치료，환자균가내수출현적불량반응，치득림상추엄。
Objective To study the clinical effects of paclitaxel carboplation chemotherapy in the treatment of ovarian cancer.Methods 92 cases of patients with ovarian cancer were divided into the control group(46 cases) and the observation group(46 cases) .The control group were treated by carboplation chemotherapy,the observation group were treated by paclitaxel carboplation chemotherapy.The clinical effects and adverse reactions rates were compared between the 2 groups.Results The to-tal effective rate of the observation group(89.13%) were higher than that of the control group(63.04%),P<0.05.There was no significant difference in the adverse reactions rate between the observation group ( 26.07%) and the control group (23.91%).Conclusion The clinical effects of paclitaxel carboplation chemotherapy in the treatment of ovarian cancer is better than the carboplation chemotherapy.The patients can tolerate the adverse reactions.It is worthy of clinical promotion.