CAJ | 학술논문

目的：了解甲状腺乳头状微灶癌（ PTMC）气管旁淋巴结转移情况，探讨临床颈淋巴结阴性（cN0）PTMC患者发生Ⅵ区淋巴转移的危险因素。方法回顾性分析行患侧甲状腺根治性切除＋颈Ⅵ区淋巴清扫术的120例cN0PTMC患者临床资料。根据术后病理检查分为Ⅵ区淋巴结转移组（40例）和未转移组（80例），并对可能的危险因素进行分析研究。结果 PTMC颈Ⅵ区淋巴结转移率为33.3％，单侧癌灶部位（ P ＜0.05）、甲状腺包膜侵犯（ P ＜0.05）、单侧多灶性PTMC（P＜0.01）为Ⅵ区淋巴结转移的危险因素。结论 cN0PTMC有较高的颈部中央组淋巴结转移率，在切除甲状腺的同时清扫颈Ⅵ区的淋巴结是十分必要的，尤其有相关危险因素者。
목적：료해갑상선유두상미조암（ PTMC）기관방림파결전이정황，탐토림상경림파결음성（cN0）PTMC환자발생Ⅵ구림파전이적위험인소。방법회고성분석행환측갑상선근치성절제＋경Ⅵ구림파청소술적120례cN0PTMC환자림상자료。근거술후병리검사분위Ⅵ구림파결전이조（40례）화미전이조（80례），병대가능적위험인소진행분석연구。결과 PTMC경Ⅵ구림파결전이솔위33.3％，단측암조부위（ P ＜0.05）、갑상선포막침범（ P ＜0.05）、단측다조성PTMC（P＜0.01）위Ⅵ구림파결전이적위험인소。결론 cN0PTMC유교고적경부중앙조림파결전이솔，재절제갑상선적동시청소경Ⅵ구적림파결시십분필요적，우기유상관위험인소자。
Objective To analyze the risk factors of central compart-ment lymph node ( CCLN) metastasis in papillary thyroid micro carcino-ma ( PTMC ) without clinical cervical lymph node metastasis ( cN0 ) , according to the general situation of paratracheal lymph node metastasis in PTMC.Methods Clinical data of 120 PTMC ( cN0 ) patients who underwent radical thyroidectomy and CCLN dissection were retrospective-ly analyzed.Patients were divided into CCLN positive group ( 40 cases ) and CCLN negative group (80 cases) according to postoperative pathology results, and the risk factors were analyzed.Results The CCLN metasta-sis rate of PTMC was 33.3%.Position ( P<0.05 ) , capsular invasion (P<0.05), multifocal PTMC (P<0.01) were the risk factors of CCLN metastasis.Conclusion The ( cN0 ) PTMC has a high rate of pathologi-cal CCLN metastasis.It is imperative to conduct the thyroidectomy with ipsilateral level Ⅵ lymph node dissection in PTMC patients , especially those with related risk factors.