中国临床药理学杂志
中國臨床藥理學雜誌
중국림상약이학잡지
THE CHINESE JOURNAL OF CLINICAL PHARMACOLOGY
2015年
2期
155-157
,共3页
叶建林%徐晓华%洪荣%朱扣柱%洪远
葉建林%徐曉華%洪榮%硃釦柱%洪遠
협건림%서효화%홍영%주구주%홍원
抗癫痫药物%治疗%儿童%发育%癫痫
抗癲癇藥物%治療%兒童%髮育%癲癇
항전간약물%치료%인동%발육%전간
antiepileptic drug%treatment%children%growth and development%epilepsy
癫痫是儿童神经系统最常见的疾病之一,目前药物治疗仍是首选方案。儿童癫痫药物治疗与成人有所不同,对不同发育阶段的儿童的癫痫治疗需特殊考虑。婴幼儿期:脏器发育不完善,抗癫痫药物的选择应考虑其安全性;学龄前期和学龄期:学习、认知和社会心理发展的关键时期,抗癫痫药物选择应充分考虑其对认知功能的影响;青春前期和青春期:抗癫痫药物治疗要考虑其长期用药对患儿生长发育各个环节的影响。因此,本文综述了其药物治疗进展及搜集了相关的循证医学证据。
癲癇是兒童神經繫統最常見的疾病之一,目前藥物治療仍是首選方案。兒童癲癇藥物治療與成人有所不同,對不同髮育階段的兒童的癲癇治療需特殊攷慮。嬰幼兒期:髒器髮育不完善,抗癲癇藥物的選擇應攷慮其安全性;學齡前期和學齡期:學習、認知和社會心理髮展的關鍵時期,抗癲癇藥物選擇應充分攷慮其對認知功能的影響;青春前期和青春期:抗癲癇藥物治療要攷慮其長期用藥對患兒生長髮育各箇環節的影響。因此,本文綜述瞭其藥物治療進展及搜集瞭相關的循證醫學證據。
전간시인동신경계통최상견적질병지일,목전약물치료잉시수선방안。인동전간약물치료여성인유소불동,대불동발육계단적인동적전간치료수특수고필。영유인기:장기발육불완선,항전간약물적선택응고필기안전성;학령전기화학령기:학습、인지화사회심리발전적관건시기,항전간약물선택응충분고필기대인지공능적영향;청춘전기화청춘기:항전간약물치료요고필기장기용약대환인생장발육각개배절적영향。인차,본문종술료기약물치료진전급수집료상관적순증의학증거。
Epilepsy is one of the most common disease of nervous sys-tem in children, and drug treatment is still the first choice at present.The treatment of children epilepsy is different from adults for there is a special consideration of epileptic therapy in different development sta-ges of children.Infancy stage:the choice of antiepileptic drugs should consider the safety for their immature internal organs.Preschool and school-age stages:the selection of antiepileptic drug should fully con-sider the effects on cognitive function for it′s the key period of development of learning, cognition, and social psychology.Pre-ado-lescence and adolescence stages:the drug therapy should consider its long-term effects on the growth of children.Therefore, the treatment of epilepsy in children needs to focus on drug efficacy and adverse re-actions in different development stages in order to provide some helps for clinic by reviewing the research advance and searching the proof of evidence-based medicine.