中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
2期
58-60
,共3页
急性呼吸衰竭%无创正压通气%有创机械通气
急性呼吸衰竭%無創正壓通氣%有創機械通氣
급성호흡쇠갈%무창정압통기%유창궤계통기
Acute respiratory failure%Noninvasive positive pressure ventilation%Invasive mechanical ventilation
目的：探讨无创正压通气（NIPPV）治疗急性呼吸衰竭患者的临床效果，为临床治疗提供依据。方法：随机选择本院2012年7月-2013年12月急性呼吸衰竭患者72例，根据患者应用通气方式分为有创机械通气组（对照组）及无创正压通气组（观察组），两组各36例。评估两组通气4 h和24 h的动脉血氧分压（PaO2）、动脉二氧化碳分压（PaCO2）和动脉血氧饱和度（SaO2）；机械通气、呼吸机相关性肺炎（VAP）发生率等指标。结果：观察组通气4 h的PaO2、PaCO2和SaO2分别为（82.77±1.68）mm Hg、（57.80±1.13）%、（77.19±5.46）%，通气24 h分别为（92.48±1.41）mm Hg、（49.85±1.02）mm Hg、（93.83±6.07）%；对照组通气4 h的PaO2、PaCO2和SaO2分别为（91.43±1.92）mm Hg、（52.37±0.81）mm Hg、（81.31±6.68）%，通气24 h分别为（94.55±1.30）mm Hg、（50.34±0.89）mm Hg、（94.02±7.96）%，两组比较通气4 h差异有统计学意义（P<0.05），而通气24 h差异无统计学意义；观察组VAP发生率为8.33%，低于对照组的27.78%，差异有统计学意义（P<0.05）；观察组住院时间为（17.19±0.46）d，低于对照组的（21.31±0.68）d，差异有统计学意义（P<0.05）。结论：NIPPV能够有效改善急性呼吸衰竭患者的气体交换，可以有效减少多种并发症的发生。
目的：探討無創正壓通氣（NIPPV）治療急性呼吸衰竭患者的臨床效果，為臨床治療提供依據。方法：隨機選擇本院2012年7月-2013年12月急性呼吸衰竭患者72例，根據患者應用通氣方式分為有創機械通氣組（對照組）及無創正壓通氣組（觀察組），兩組各36例。評估兩組通氣4 h和24 h的動脈血氧分壓（PaO2）、動脈二氧化碳分壓（PaCO2）和動脈血氧飽和度（SaO2）；機械通氣、呼吸機相關性肺炎（VAP）髮生率等指標。結果：觀察組通氣4 h的PaO2、PaCO2和SaO2分彆為（82.77±1.68）mm Hg、（57.80±1.13）%、（77.19±5.46）%，通氣24 h分彆為（92.48±1.41）mm Hg、（49.85±1.02）mm Hg、（93.83±6.07）%；對照組通氣4 h的PaO2、PaCO2和SaO2分彆為（91.43±1.92）mm Hg、（52.37±0.81）mm Hg、（81.31±6.68）%，通氣24 h分彆為（94.55±1.30）mm Hg、（50.34±0.89）mm Hg、（94.02±7.96）%，兩組比較通氣4 h差異有統計學意義（P<0.05），而通氣24 h差異無統計學意義；觀察組VAP髮生率為8.33%，低于對照組的27.78%，差異有統計學意義（P<0.05）；觀察組住院時間為（17.19±0.46）d，低于對照組的（21.31±0.68）d，差異有統計學意義（P<0.05）。結論：NIPPV能夠有效改善急性呼吸衰竭患者的氣體交換，可以有效減少多種併髮癥的髮生。
목적：탐토무창정압통기（NIPPV）치료급성호흡쇠갈환자적림상효과，위림상치료제공의거。방법：수궤선택본원2012년7월-2013년12월급성호흡쇠갈환자72례，근거환자응용통기방식분위유창궤계통기조（대조조）급무창정압통기조（관찰조），량조각36례。평고량조통기4 h화24 h적동맥혈양분압（PaO2）、동맥이양화탄분압（PaCO2）화동맥혈양포화도（SaO2）；궤계통기、호흡궤상관성폐염（VAP）발생솔등지표。결과：관찰조통기4 h적PaO2、PaCO2화SaO2분별위（82.77±1.68）mm Hg、（57.80±1.13）%、（77.19±5.46）%，통기24 h분별위（92.48±1.41）mm Hg、（49.85±1.02）mm Hg、（93.83±6.07）%；대조조통기4 h적PaO2、PaCO2화SaO2분별위（91.43±1.92）mm Hg、（52.37±0.81）mm Hg、（81.31±6.68）%，통기24 h분별위（94.55±1.30）mm Hg、（50.34±0.89）mm Hg、（94.02±7.96）%，량조비교통기4 h차이유통계학의의（P<0.05），이통기24 h차이무통계학의의；관찰조VAP발생솔위8.33%，저우대조조적27.78%，차이유통계학의의（P<0.05）；관찰조주원시간위（17.19±0.46）d，저우대조조적（21.31±0.68）d，차이유통계학의의（P<0.05）。결론：NIPPV능구유효개선급성호흡쇠갈환자적기체교환，가이유효감소다충병발증적발생。
Objective:To explore the clinical research on patients with acute respiratory failure treated by noninvasive positive pressure ventilation(NIPPV) and provide the clinical basis.Method:72 patients with acute respiratory failure were selected randomly from July 2012 to December 2013 in our hospital. According to the application of ventilation, they were divided into invasive mechanical ventilation group(the control group) and noninvasive positive pressure ventilation group (the observation group), which were 36 cases in each groups respectively. The main assessment indexes of two groups were PaO2, PaCO2 and SaO2 after 4 h and 24 h ventilation; mechanical ventilation, VAP occurrence rate.Result:In the observation group,4 h PaO2, PaCO2 ventilation and SaO2 were (82.77±1.68)mm Hg, (57.80±1.13)mm Hg,(77.19±5.46)%;24 h PaO2, ventilation PaCO2 and SaO2 were (92.48±1.41)mm Hg, (49.85±1.02)mm Hg,(93.83±6.07)%.In the control group,PaO2, PaCO2 4 h ventilation and SaO2 were (91.43±1.92)mm Hg,(52.37±0.81)mm Hg,(81.31±6.68)%,24 h PaO2,PaCO2 ventilation and SaO2 were (94.55±1.30)mm Hg,(50.34±0.89)mm Hg,(94.02±7.96)%,there was a statistically significant difference in ventilation 4 hours between the two groups(P<0.05), there was no significant differences in ventilation 24 hours.The incidence of VAP in the observation group was 8.33%, which was lower than 27.78% in the control group, the difference was statistically significant(P<0.05).Hospital stay in the observation group was (17.19±0.46)d, which was lower than (21.31±0.68)d in the control group, the difference was statistically significant(P<0.05).Conclusion:NIPPV could effectively improve the gas exchange of the patients with acute respiratory failure, without the need for tracheotomy, effectively avoid various complications occurred.
