中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
2期
129-131
,共3页
新生儿%黄疸%微生态制剂%双歧三联活菌制剂
新生兒%黃疸%微生態製劑%雙歧三聯活菌製劑
신생인%황달%미생태제제%쌍기삼련활균제제
The newborn%Jaundice%Probiotics%The colon triple living bacteria preparation
目的：评价与分析微生态制剂治疗应用于新生儿黄疸中的临床疗效及安全性。方法：按照随机抽签法将本次68例新生儿黄疸分为对照组与治疗组各34例。对照组采用蓝光照射等治疗；治疗组在对照组治疗基础上加用微生态双歧三联活菌制剂治疗。于治疗前和治疗第1、4、7天检测两组患者血清总胆红素水平，统计两组临床药物起效时间和黄疸消退时间及临床疗效、不良反应。结果：治疗前，两组血清胆红素水平比较差异无统计学意义（P>0.05）；治疗第1、4、7天两组血清胆红素水平较治疗前均明显下降（P<0.05）；但第1天两组组间比较差异无统计学意义（P>0.05）；第4、7天治疗组下降更为明显，与对照组比较差异有统计学意义（P<0.05）。治疗组临床药物起效时间和黄疸消退时间分别为（1.0±0.5）d、（3.8±1.7）d，与对照组（2.6±0.6）d、（5.3±2.1）d比较差异有统计学意义（P<0.05）。治疗组治疗有效率明显高于对照组（P<0.05）；两组均未发生明显不良反应。结论：采用微生态制剂治疗新生儿黄疸，其可明显降低患者血清胆红素，且起效快，加速患者黄疸消退，且具有较高安全性，值得推广与应用。
目的：評價與分析微生態製劑治療應用于新生兒黃疸中的臨床療效及安全性。方法：按照隨機抽籤法將本次68例新生兒黃疸分為對照組與治療組各34例。對照組採用藍光照射等治療；治療組在對照組治療基礎上加用微生態雙歧三聯活菌製劑治療。于治療前和治療第1、4、7天檢測兩組患者血清總膽紅素水平，統計兩組臨床藥物起效時間和黃疸消退時間及臨床療效、不良反應。結果：治療前，兩組血清膽紅素水平比較差異無統計學意義（P>0.05）；治療第1、4、7天兩組血清膽紅素水平較治療前均明顯下降（P<0.05）；但第1天兩組組間比較差異無統計學意義（P>0.05）；第4、7天治療組下降更為明顯，與對照組比較差異有統計學意義（P<0.05）。治療組臨床藥物起效時間和黃疸消退時間分彆為（1.0±0.5）d、（3.8±1.7）d，與對照組（2.6±0.6）d、（5.3±2.1）d比較差異有統計學意義（P<0.05）。治療組治療有效率明顯高于對照組（P<0.05）；兩組均未髮生明顯不良反應。結論：採用微生態製劑治療新生兒黃疸，其可明顯降低患者血清膽紅素，且起效快，加速患者黃疸消退，且具有較高安全性，值得推廣與應用。
목적：평개여분석미생태제제치료응용우신생인황달중적림상료효급안전성。방법：안조수궤추첨법장본차68례신생인황달분위대조조여치료조각34례。대조조채용람광조사등치료；치료조재대조조치료기출상가용미생태쌍기삼련활균제제치료。우치료전화치료제1、4、7천검측량조환자혈청총담홍소수평，통계량조림상약물기효시간화황달소퇴시간급림상료효、불량반응。결과：치료전，량조혈청담홍소수평비교차이무통계학의의（P>0.05）；치료제1、4、7천량조혈청담홍소수평교치료전균명현하강（P<0.05）；단제1천량조조간비교차이무통계학의의（P>0.05）；제4、7천치료조하강경위명현，여대조조비교차이유통계학의의（P<0.05）。치료조림상약물기효시간화황달소퇴시간분별위（1.0±0.5）d、（3.8±1.7）d，여대조조（2.6±0.6）d、（5.3±2.1）d비교차이유통계학의의（P<0.05）。치료조치료유효솔명현고우대조조（P<0.05）；량조균미발생명현불량반응。결론：채용미생태제제치료신생인황달，기가명현강저환자혈청담홍소，차기효쾌，가속환자황달소퇴，차구유교고안전성，치득추엄여응용。
Objective:To evaluate and analyze clinical curative effect and safety of probiotics treatment applied in neonatal jaundice.Method:According to the method of random draw,68 cases of neonatal jaundice were divided into control group and treatment group, 34 cases in each. The control group were treated with blue light treatment;the treatment group were treated with micro ecological dichotomous triple living bacteria preparation treatment on the basis of the control group. In before and 1, 4, 7 d treatment serum total bilirubin level detection of two groups of patients, the statistics of two groups of clinical drug effect time and jaundice subsided and clinical curative effect and adverse reactions. Result: Before the treatment, two groups of serum bilirubin level comparison (P>0.05).Treatment of 1, 4, 7 d, two groups of serum bilirubin level before treatment were significantly decreased(P<0.05).But 1 d, 2 way comparison (P>0.05);4, 7 d treatment group decreased more significantly, compared with the control group(P<0.05).Clinical drug treatment group effect and presented a time respectively (1.0±0.5) d with the control group,(3.8±1.7)d, (2.6±0.6)d,(5.3±2.1)d comparison(P<0.05).Treatment of efficient treatment group was obviously higher than that of control group(P<0.05).Two groups were not obvious adverse reactions.Conclusion:Using probiotics to treat neonatal jaundice,and it can obviously reduce the patients’ serum bilirubin, and take effect quickly, accelerate the patients with jaundice subsided, and has high security, is worthy of popularization and application.
