CAJ | 학술논문

目的：探讨间苯三酚联合缩宫素对足月妊娠引产的效果及安全性。方法采用随机双盲、对照研究的方法，将足月妊娠中低宫颈评分的204例孕妇随机分为两组：观察组102例应用间苯三酚联合缩宫素引产，对照组102例静脉滴注缩宫素引产。结果观察组子宫颈口扩张速度明显快于对照组(P＜0.05)，第一产程和总产程时间显著少于对照组(P＜0.01)，阴道分娩率明显高于对照组(P＜0.05)，而两组第二产程时间、第三产程时间、新生儿阿氏评分、出生体重、产妇产后2 h的出血量对比差异无统计学意义（P＞0.05），母儿无不良结局。结论间苯三酚联合缩宫素可更加有效地促进宫颈成熟、显著缩短产程、增加阴道分娩机会，效果优于单纯应用缩宫素，且安全，值得推广。
목적：탐토간분삼분연합축궁소대족월임신인산적효과급안전성。방법채용수궤쌍맹、대조연구적방법，장족월임신중저궁경평분적204례잉부수궤분위량조：관찰조102례응용간분삼분연합축궁소인산，대조조102례정맥적주축궁소인산。결과관찰조자궁경구확장속도명현쾌우대조조(P＜0.05)，제일산정화총산정시간현저소우대조조(P＜0.01)，음도분면솔명현고우대조조(P＜0.05)，이량조제이산정시간、제삼산정시간、신생인아씨평분、출생체중、산부산후2 h적출혈량대비차이무통계학의의（P＞0.05），모인무불량결국。결론간분삼분연합축궁소가경가유효지촉진궁경성숙、현저축단산정、증가음도분면궤회，효과우우단순응용축궁소，차안전，치득추엄。
ObjectiveTo study the efficacy and safety of using phloroglucinol with oxytocin in full-term pregnancy induced labor.MethodsUsing randomized double-blind and controlled study ways, 204 pregnant women who got middle and lower cervical score of full-term pregnancy were randomly divided into 2 groups: Observation group, of which 102 cases were performed induced labor by phloroglucinol with oxytocin, and control group, of which 102 cases were performed induced labor by intravenous drip of oxytocin.ResultsThe cervix expansion speed of observation group was obviously faster than the control group (P<0.05). The first stage of labor and total labor time was significantly less than the control group (P<0.01). Vaginal births were significantly higher than the control group (P<0.05). There was no statistical significance contrasting the time of second and three stage of labor, Apgar scores, birth weight, and postpartum hemorrhage after 2 hours (P>0.05). There were no adverse outcomes with mother and baby.ConclusionThe phloroglucinol with oxytocin could be more effective in promoting cervical ripening, significantly shortening the production process and increasing the chance of vaginal delivery. The effect was better than the simple application of oxytocin. And the drug was safe, worth popularizing in obstetrics .