CAJ | 학술논문

目的：探讨小细胞肺癌的临床病理特点以及不同性别的差异表现。方法回顾性分析75例小细胞肺癌患者的临床病理资料。结果男性62例，女性13例，平均年龄（64．6±11．2）岁，两种性别的发病高峰期均为60～69岁，两者比较无统计学差异（P＞0．05）。有吸烟史48例（64．0％），男性所占比率明显高于女性，存在统计学意义（P＜0．05）。城市与乡镇发病比例为2．17∶1，主要以LD、中心型为主，不同性别间比较无统计学差异（P＞0．05）。首发症状包括咳嗽、咳痰、发热、胸闷气短、胸部疼痛以及肺外症状，不同性别间首发症状比较均存在统计学差异（P＜0．05）。病变位置于右肺上叶与左肺上叶最多，其中男性患者中以右肺上叶最为多见，女性患者为右肺下叶最为多见，略有差异。结论小细胞肺癌发病以男性为主，而吸烟史是该疾病的最主要危险因素之一，肿瘤多位于右肺上叶。
목적：탐토소세포폐암적림상병리특점이급불동성별적차이표현。방법회고성분석75례소세포폐암환자적림상병리자료。결과남성62례，녀성13례，평균년령（64．6±11．2）세，량충성별적발병고봉기균위60～69세，량자비교무통계학차이（P＞0．05）。유흡연사48례（64．0％），남성소점비솔명현고우녀성，존재통계학의의（P＜0．05）。성시여향진발병비례위2．17∶1，주요이LD、중심형위주，불동성별간비교무통계학차이（P＞0．05）。수발증상포괄해수、해담、발열、흉민기단、흉부동통이급폐외증상，불동성별간수발증상비교균존재통계학차이（P＜0．05）。병변위치우우폐상협여좌폐상협최다，기중남성환자중이우폐상협최위다견，녀성환자위우폐하협최위다견，략유차이。결론소세포폐암발병이남성위주，이흡연사시해질병적최주요위험인소지일，종류다위우우폐상협。
Objective To investigate the clinical and pathological features of small cell lung cancer and gender differ-ences.Methods Clinical data of 75 cases of small cell lung cancer were retrospectively analyzed.Results 62 were male and 13 female,mean age (64.6 ±11.2)years,the peak incidence of both gender were 60~69 years old,there was no significant differ-ence between the 2 groups (P>0.05).There had 48 cases of patients with history of smoking (64.0%),the percentage of male was higher than female,there was statistically significant difference (P<0.05).Incidence ratio between cities and towns was 2.17:1,mainly was LD,central type,there had no significant difference (P>0.05)between the 2 sexes.Initial symptoms includ-ed cough,sputum,fever,chest tightness,shortness of breath,chest pain,and pulmonary symptoms,there had significant difference (P<0.05)between the 2 sexes.Location of the lesion was mainly on the right upper lobe and the left upper lobe,male patients was mainly on the right upper lobe,and female patients was mainly on the right lower lobe,there had slight difference.Conclusion Small cell lung cancer is male-dominated in the pathogenesis,and smoking is one of the most important risk factor,the tumor is mainly in the right upper lobe.