CAJ | 학술논문

目的：探讨右美托咪定自控镇静与Narcotrend值的相关性。方法：选择下肢择期手术患者40例，腰硬联合麻醉阻滞平面固定后，采用电子泵予患者右美托咪定自控镇静，电子泵参数为：负荷量2 mL＋背景输注量1．5 mL／h＋单次剂量0．5 mL＋锁定时间20 s。记录患者 HR、MAP、按压次数、有效次数、OAA／S镇静评分和NI值。结果：在T4点时，患者达到适宜镇静状态，在T4～T9点OAA／S评分维持3～4分。从T5点开始，患者NI值表现出明显下降，于T7点后维持相对稳定NI值（60～70）。 OAA／S 评分和NI值达到平台期的时间分别为（7．5±1．8）、（13．1±3．4） min，OAA／S 评分的1、2、3、4分大致分别与 NI 值的95～100、90～94、65～89、40～64相对应，相关系数为0．58。年轻组和年老组的NI值出现明显下降的时间分别为（10．2±1．6）、（14．4±2．2） min。在T5～T9时间点，年轻组的NI值显著低于年老组。结论：腰硬联合麻醉下右美托咪定自控镇静深度与Narcotrend值具有相关性。
목적：탐토우미탁미정자공진정여Narcotrend치적상관성。방법：선택하지택기수술환자40례，요경연합마취조체평면고정후，채용전자빙여환자우미탁미정자공진정，전자빙삼수위：부하량2 mL＋배경수주량1．5 mL／h＋단차제량0．5 mL＋쇄정시간20 s。기록환자 HR、MAP、안압차수、유효차수、OAA／S진정평분화NI치。결과：재T4점시，환자체도괄의진정상태，재T4～T9점OAA／S평분유지3～4분。종T5점개시，환자NI치표현출명현하강，우T7점후유지상대은정NI치（60～70）。 OAA／S 평분화NI치체도평태기적시간분별위（7．5±1．8）、（13．1±3．4） min，OAA／S 평분적1、2、3、4분대치분별여 NI 치적95～100、90～94、65～89、40～64상대응，상관계수위0．58。년경조화년로조적NI치출현명현하강적시간분별위（10．2±1．6）、（14．4±2．2） min。재T5～T9시간점，년경조적NI치현저저우년로조。결론：요경연합마취하우미탁미정자공진정심도여Narcotrend치구유상관성。
Objective To explore the correlation of patient-controlled sedation of dexmedetomidine and Narcotrend values. Methods Forty patients with lower limb surgery were enrolled. Until CSEA block fixed , the electronic pump ran the patient-controlled sedation of dexmedetomidine. The parameter of electronic pump was set as follows: load dose 2 mL + background dose 1.5 mL/h + single dose 0.5 mL + locktime 20 s. The heart rate , mean arterial pressure, pressing times, effective times, OAA/S sedation scores and NI values were determined. Results At T4 point, the patients reached appropriate sedation. At T4 ~ T9 OAA/S scores kept 3 to 4. From T5 point, NI values showed significant decrease. After the T7 point. OAA/S scores and NI values reached the plateau time of (7.5 ± 1.8) min and (13.1 ± 3.4) min, OAA/S scores of 1, 2, 3, 4, respectively, corresponding roughly with NI values 95 to 100, 90 to 94, 65 to 89, 40 to 64. The correlation coefficient was 0.58. The time of NI values significant decreased in the younger group and in the elderly group, with (10.2 ± 1.6) min and (14.4 ± 2.2) min. In T5~ T9 point, NI values of the younger group were significantly lower than those in the elderly group. Conclusion Relevant relationships are observed between dexmedetomidine patient-controlled sedation depth and the narcotrend values under CSEA.