现代诊断与治疗
現代診斷與治療
현대진단여치료
MODERN DIAGNOSIS AND TREATMENT
2014年
18期
4100-4101,4102
,共3页
还原型谷胱甘肽%慢性乙型肝炎%疗效分析
還原型穀胱甘肽%慢性乙型肝炎%療效分析
환원형곡광감태%만성을형간염%료효분석
Reduced glutathione%Chronic hepatitis B%Clinical analysis
目的：探讨分析应用还原型谷胱甘肽治疗慢性乙型肝炎的临床效果，为其临床应用提供理论依据。方法选取2013年1月～2014年1月来我院治疗的慢性乙型肝炎患者102例，随机分为观察组和对照组，每组各51例。观察组与对照组均给与常规护肝治疗，在此治疗基础上，观察组加用还原型谷胱甘肽，对照组加用门冬氨酸镁钾。观察两组患者的临床症状体征和相关生化指标、并发症发生率、治疗总有效率、肝功能水平与肝功能恢复正常时间。结果经过治疗，观察组临床表现和相关生化指标改善情况、并发症发生率、治疗总有效率、肝功能恢复正常时间显著优于对照组，差异明显，均有统计学意义（P<0.05）。结论还原型谷胱甘肽能够保护肝功能，降低血浆肝酶水平，有效治疗慢性乙型肝炎，减少并发症发生率，缩短治疗时间，值得临床推广应用。
目的：探討分析應用還原型穀胱甘肽治療慢性乙型肝炎的臨床效果，為其臨床應用提供理論依據。方法選取2013年1月～2014年1月來我院治療的慢性乙型肝炎患者102例，隨機分為觀察組和對照組，每組各51例。觀察組與對照組均給與常規護肝治療，在此治療基礎上，觀察組加用還原型穀胱甘肽，對照組加用門鼕氨痠鎂鉀。觀察兩組患者的臨床癥狀體徵和相關生化指標、併髮癥髮生率、治療總有效率、肝功能水平與肝功能恢複正常時間。結果經過治療，觀察組臨床錶現和相關生化指標改善情況、併髮癥髮生率、治療總有效率、肝功能恢複正常時間顯著優于對照組，差異明顯，均有統計學意義（P<0.05）。結論還原型穀胱甘肽能夠保護肝功能，降低血漿肝酶水平，有效治療慢性乙型肝炎，減少併髮癥髮生率，縮短治療時間，值得臨床推廣應用。
목적：탐토분석응용환원형곡광감태치료만성을형간염적림상효과，위기림상응용제공이론의거。방법선취2013년1월～2014년1월래아원치료적만성을형간염환자102례，수궤분위관찰조화대조조，매조각51례。관찰조여대조조균급여상규호간치료，재차치료기출상，관찰조가용환원형곡광감태，대조조가용문동안산미갑。관찰량조환자적림상증상체정화상관생화지표、병발증발생솔、치료총유효솔、간공능수평여간공능회복정상시간。결과경과치료，관찰조림상표현화상관생화지표개선정황、병발증발생솔、치료총유효솔、간공능회복정상시간현저우우대조조，차이명현，균유통계학의의（P<0.05）。결론환원형곡광감태능구보호간공능，강저혈장간매수평，유효치료만성을형간염，감소병발증발생솔，축단치료시간，치득림상추엄응용。
Objective To investigate the clinical effect of reduced glutathione in the treatment of chron-ic hepatitis B, to provide theoretical basis for its clinical application. Methods 102 patients with chronic hepatitis B from 2013 January to 2014 January in our hospital, were randomly divided into ob-servation group and control group, each group of 51 cases. The observation group and the control group were given conventional treatment, based on this treatment, observation group were treated with reduced glutathione, control group were treated with potassium magnesium aspartate. Clinical symptoms and signs and correlative biochemical indexes, incidence of complications, the total efficiency of treatment, liver function and liver function returned to normal time were observed in patients of two groups. Re-sults After the treatment, clinical manifestations and related biochemical indicators of the observation group to improve the situation, complication rate, the total efficiency of treatment, liver function recov-ery time were significantly better than the control group, the difference was statistically significant (P<0.05). Conclusion Glutathione can protect the liver function, reduce the levels of liver enzymes in plasma, be effective in the treatment of chronic hepatitis B, reduce the incidence of complications, short the duration of treatment, be worthy of clinical application.
