CAJ | 학술논문

目的：研究参元益气活血胶囊联合早期冠脉介入对不稳定型心绞痛患者近期生活质量的影响。方法：78例不稳定型心绞痛患者随机分为治疗组和对照组，各39例，冠状动脉造影后行早期冠状动脉介入治疗（PCI）术，术前对照组给予常规西药治疗，治疗组给予常规西药治疗加参元益气活血胶囊，每次3粒，每日3次，疗程30天。治疗前后对两组患者生活质量进行评分，判定心绞痛、心电图及中医主症疗效。结果：与治疗前相比，两组患者治疗后躯体活动受限程度、心绞痛稳定状态、心绞痛发作情况、治疗满意程度计分均明显升高（P<0.05）；与对照组比较，参元益气活血胶囊治疗组治疗后心绞痛发作频率、持续时间以及心悸、乏力、气短症状均明显改善（P<0.05），治疗组心绞痛稳定状态、心绞痛发作情况、治疗满意程度计分均明显升高（P<0.05）。结论：参元益气活血胶囊联合早期PCI治疗可以提高不稳定型心绞痛患者的近期生活质量和中医主症。
목적：연구삼원익기활혈효낭연합조기관맥개입대불은정형심교통환자근기생활질량적영향。방법：78례불은정형심교통환자수궤분위치료조화대조조，각39례，관상동맥조영후행조기관상동맥개입치료（PCI）술，술전대조조급여상규서약치료，치료조급여상규서약치료가삼원익기활혈효낭，매차3립，매일3차，료정30천。치료전후대량조환자생활질량진행평분，판정심교통、심전도급중의주증료효。결과：여치료전상비，량조환자치료후구체활동수한정도、심교통은정상태、심교통발작정황、치료만의정도계분균명현승고（P<0.05）；여대조조비교，삼원익기활혈효낭치료조치료후심교통발작빈솔、지속시간이급심계、핍력、기단증상균명현개선（P<0.05），치료조심교통은정상태、심교통발작정황、치료만의정도계분균명현승고（P<0.05）。결론：삼원익기활혈효낭연합조기PCI치료가이제고불은정형심교통환자적근기생활질량화중의주증。
This study was aimed to investigate the effects of Shen-Y uan Y i-Qi Huo-Xue (SYYQHX) capsule com-bined with early percutaneous coronary intervention (PCI) on near-term quality of life (QOL) in unstable angina (UA) patients. Seventy-eight patients diagnosed with UA were selected and randomly divided into the treatment group and control group, with 39 patients in each group. Early PCI was undergone after coronary angiography. Before PCI, the control group was given routine western medication. The treatment group was given routine western medication plus SYYQHX capsule, three pills once, three times daily. The treatment lasted for 30 days. The QOL scores were evalu-ated among patients from both groups before and after treatment in order to determine the efficacy on angina, electro-cardiogram (ECG) and traditional Chinese medicine (TCM) main symptom. The results showed that compared to pre-treatment, the scores of physical limitation (PL), angina stability (AS), angina frequency (AF), and treatment satisfac-tion ( TS ) were significantly increased after treatment ( P < 0 . 05 ) . Compared with the control group , after treat-ment with SYYQHX capsule, the AF, duration time and symptoms of palpitation, fatigue and shortness of breath were obviously improved (P< 0.05). The scores of AS, AF and TS in the treatment group were significantly increased (P < 0.05). It was concluded that SYYQHX capsule combined with early PCI can improve the near-term QOL and TCM main symptoms among UA patients.