CAJ | 학술논문

随着中药现代化的不断深入，对中药定量化、标准化，即对中药的定量表征，已日益得到研究人员的广泛认同。而化学计量学通过应用数学、统计学和计算机技术的原理和方法来处理中药的复杂数据，并将多变量的研究引入其中从而良好地对中药进行定量表征，更是取得了较大的进展。该文对近年来中药定量表征中存在的问题、主要化学计量学方法的原理、特点、局限性及常用统计方法以及其在中药定量表征中的应用现状进行综述，以期对深入研究中药定量表征提供参考，为多种化学计量学方法的结合使用提供进一步的研究思路。
수착중약현대화적불단심입，대중약정양화、표준화，즉대중약적정량표정，이일익득도연구인원적엄범인동。이화학계량학통과응용수학、통계학화계산궤기술적원리화방법래처리중약적복잡수거，병장다변량적연구인입기중종이량호지대중약진행정량표정，경시취득료교대적진전。해문대근년래중약정량표정중존재적문제、주요화학계량학방법적원리、특점、국한성급상용통계방법이급기재중약정량표정중적응용현상진행종술，이기대심입연구중약정량표정제공삼고，위다충화학계량학방법적결합사용제공진일보적연구사로。
With the deepening of modernization of traditional Chinese medicine (TCM), the method of quantification and standardization of TCM (i.e., quantitative characterization of TCM) has been more and more widely accepted by researchers. Chemometrics processes complicated data of TCM through applied mathematics, statistics and com-puter technology. And multivariable study was introduced into the quantitative characterization of TCM with great achievements. This article reviewed existed problems of quantitative characterization in TCM, the principles, char-acteristics, limitations, commonly used statistical methods and application conditions on quantitative characteriza-tion of TCM. With this review, a reference for further study of quantitative characterization of TCM was provided and a further research idea of combination with main methods of chemometrics was given.