CAJ | 학술논문

目的：通过对银杏二萜内酯葡胺注射液与中性硼硅玻璃安瓿的药物相容性试验研究，确定中性硼硅玻璃安瓿作为银杏二萜内酯葡胺注射液内包装材料的可行性。方法：根据《药品包装材料与药物相容性试验指导原则》，进行以中性硼硅玻璃安瓿为包装材料的银杏二萜内酯葡胺注射液相容性研究。结果：中性硼硅玻璃安瓿与银杏二萜内酯葡胺注射液之间无迁移及吸附等质量变化，中性硼硅玻璃安瓿与银杏二萜内酯葡胺注射液具有较好的药物相容性。结论：中性硼硅玻璃安瓿可以作为银杏二萜内酯葡胺注射液的包装材料。
목적：통과대은행이첩내지포알주사액여중성붕규파리안부적약물상용성시험연구，학정중성붕규파리안부작위은행이첩내지포알주사액내포장재료적가행성。방법：근거《약품포장재료여약물상용성시험지도원칙》，진행이중성붕규파리안부위포장재료적은행이첩내지포알주사액상용성연구。결과：중성붕규파리안부여은행이첩내지포알주사액지간무천이급흡부등질량변화，중성붕규파리안부여은행이첩내지포알주사액구유교호적약물상용성。결론：중성붕규파리안부가이작위은행이첩내지포알주사액적포장재료。
This article was aimed to determine the feasibility of neutral borosilicate glass ampoule as the inner packing material of Ginkgolides meglumine injection by studying the drug compatibility between Ginkgolides me-glumine injection and neutral borosilicate glass ampoule. On the basis of the Pharmaceutical Packaging Materials and Drug Compatibility Test Guidance Rules, the study was carried on the compatibility between Ginkgolides me-glumine injection and neutral borosilicate glass ampoule for packaging materials. The results showed that no mi-gration or adsorption quality of change between the Ginkgolides meglumine injection and neutral borosilicate glass ampoule. It had good compatibility between neutral borosilicate glass ampoule and Ginkgolides meglumine injec-tion. It was concluded that neutral borosilicate glass can be used as the packing materials of Ginkgolides meglumine injection.