中国神经精神疾病杂志
中國神經精神疾病雜誌
중국신경정신질병잡지
CHINESE JOURNAL OF NERVOUS AND MENTAL DISEASES
2014年
10期
616-619
,共4页
李宗琴%陈秀%荣本兵%李倩妮%肖兴莉%李意蝶
李宗琴%陳秀%榮本兵%李倩妮%肖興莉%李意蝶
리종금%진수%영본병%리천니%초흥리%리의접
脑卒中%青年%病因%危险因素
腦卒中%青年%病因%危險因素
뇌졸중%청년%병인%위험인소
Stroke%Young adults%Etiology%Risk factors
目的：调查四川南部地区青年脑卒中病因及危险因素，为该区域脑卒中防治提供理论依据。方法回顾性分析泸州医学院附属医院神经内科2009～2013年间脑卒中患者（18～44岁）398例，并随机抽取同期年龄≥45岁脑卒中425例作对照，分析病因及危险因素。结果①青年脑卒中占同期脑卒中患者的6.09%，其中缺血性卒中78.39%；男64.57%；40～44岁占58.04%。②TOAST病因分型：大动脉粥样硬化型（56.09%）、小动脉闭塞型（17.95%）、心源性（9.93%）、其他原因型（10.90%）及不明原因型（5.13%），其中青年组其他原因型及不明原因型均高于中老年组，而小动脉闭塞型低于中老年组（P＜0.05）。出血性卒中高血压性脑出血（50%），其中各型与中老年组比较（P＞0.05）。③危险因素分析：青年组中吸烟（34.92%）、高脂血症（31.41%）、饮酒（20.10%）、肥胖（13.07%）、风心病（6.03%）构成比均高于中老年组，而中老年组中高血压（66.12%）、糖尿病（20.47%）、冠心病（10.82%）构成比则明显高于青年组（P＜0.05）。结论大动脉粥样硬化型是该区域青年缺血性脑卒中最常见的分型，出血性脑卒中以高血压性最常见；最常见的危险因素为高血压、吸烟及高脂血症。
目的：調查四川南部地區青年腦卒中病因及危險因素，為該區域腦卒中防治提供理論依據。方法迴顧性分析瀘州醫學院附屬醫院神經內科2009～2013年間腦卒中患者（18～44歲）398例，併隨機抽取同期年齡≥45歲腦卒中425例作對照，分析病因及危險因素。結果①青年腦卒中佔同期腦卒中患者的6.09%，其中缺血性卒中78.39%；男64.57%；40～44歲佔58.04%。②TOAST病因分型：大動脈粥樣硬化型（56.09%）、小動脈閉塞型（17.95%）、心源性（9.93%）、其他原因型（10.90%）及不明原因型（5.13%），其中青年組其他原因型及不明原因型均高于中老年組，而小動脈閉塞型低于中老年組（P＜0.05）。齣血性卒中高血壓性腦齣血（50%），其中各型與中老年組比較（P＞0.05）。③危險因素分析：青年組中吸煙（34.92%）、高脂血癥（31.41%）、飲酒（20.10%）、肥胖（13.07%）、風心病（6.03%）構成比均高于中老年組，而中老年組中高血壓（66.12%）、糖尿病（20.47%）、冠心病（10.82%）構成比則明顯高于青年組（P＜0.05）。結論大動脈粥樣硬化型是該區域青年缺血性腦卒中最常見的分型，齣血性腦卒中以高血壓性最常見；最常見的危險因素為高血壓、吸煙及高脂血癥。
목적：조사사천남부지구청년뇌졸중병인급위험인소，위해구역뇌졸중방치제공이론의거。방법회고성분석로주의학원부속의원신경내과2009～2013년간뇌졸중환자（18～44세）398례，병수궤추취동기년령≥45세뇌졸중425례작대조，분석병인급위험인소。결과①청년뇌졸중점동기뇌졸중환자적6.09%，기중결혈성졸중78.39%；남64.57%；40～44세점58.04%。②TOAST병인분형：대동맥죽양경화형（56.09%）、소동맥폐새형（17.95%）、심원성（9.93%）、기타원인형（10.90%）급불명원인형（5.13%），기중청년조기타원인형급불명원인형균고우중노년조，이소동맥폐새형저우중노년조（P＜0.05）。출혈성졸중고혈압성뇌출혈（50%），기중각형여중노년조비교（P＞0.05）。③위험인소분석：청년조중흡연（34.92%）、고지혈증（31.41%）、음주（20.10%）、비반（13.07%）、풍심병（6.03%）구성비균고우중노년조，이중노년조중고혈압（66.12%）、당뇨병（20.47%）、관심병（10.82%）구성비칙명현고우청년조（P＜0.05）。결론대동맥죽양경화형시해구역청년결혈성뇌졸중최상견적분형，출혈성뇌졸중이고혈압성최상견；최상견적위험인소위고혈압、흡연급고지혈증。
Objective To investigate the etiology and risk factors of stroke in young adults from Southern Sichuan, China to provide a basis for prevention and treatment of stroke. Methods The data of 398 young patients with first-ever stroke (aged 18 to 44) admitted to department of Neurology, the Affiliated Hospital of Luzhou Medical College from 2009 to 2013 was retrospectively analyzed. Four hundred twenty-five cases of stroke (aged greater than or equal to 45) were re?cruited by stratified random sampling to analyze its causes and risk factors in the same period. Results ① Young stroke accounted for 6.09% of all hospitalized stroke patients in which 78.39% of young stroke was ischemic, 64.57%was male and 58.04% aged from 40 to 44. ② According to TOAST etiology classification group, the percentage of large-artery atherosclerosis, small-vessel, cardioembolism, other determined and undetermined reasons were 56.09%, 17.95%, 9.93%, 10.90% and 5.13% in young stroke, respectively. Compared with the elderly group, other determined and undetermined reasons were higher, and the small-vessel was lower in young stroke (P<0.05). Hypertensive cerebral hemorrhage accounted for 50%of Hemorrhage in young group, and the type of Hemorrhage between two groups was no statistically significant.(P>0.05).③ Risk factors analysis revealed that the constituent ratio of smoking (34.92%), hyper?lipidemia (31.41%), alcohol (20.10%), obesity (13.07%), rheumatic heart disease (6.03%) in youth group were higher whereas hypertension(66.12%), diabetes(20.47%)and coronary heart disease(10.82%)were lower in young stroke com?pared with the elderly group (P<0.05). Conclusion ①Large-artery atherosclerosis is the most common etiology of youth ischemic stroke. ② Hypertensive cerebral hemorrhage is the most frequent type in Hemorrhagic stroke. ③ Hyperten?sion, smoking and hyperlipidemia are the most common risk factors to stroke.
