CAJ | 학술논문

目的：探讨鼓膜置管灌注甲泼尼龙联合鼓室充气治疗难治性梅尼埃病的疗效。方法回顾性分析2011年8月—2012年8月在邯郸市第三医院住院治疗的12例单侧难治性梅尼病患者，在耳内镜下行鼓膜置管后，鼓室灌注甲泼尼龙联合鼓气耳镜进行鼓室充气治疗，观测患者眩晕、听力及耳鸣变化18-24个月。结果眩晕完全控制2例，基本控制7例，部分控制2例，无明显变化1例。听力0.5、1、2、3KHz气导平均听阈值提高10dBHL2例，提高5 dBHL3例，听力未改善6例，1例听力下降10dBHL。耳鸣消失者4例，明显减轻者6例，无明显变化者2例。结论应用鼓膜置管灌注甲泼尼龙联合鼓室充气治疗难治性梅尼埃病，短期可有效的控制眩晕，明显改善耳鸣，听力改善不明显。对于常规药物治疗无效的MD患者，选择鼓膜置管灌注甲泼尼龙联合鼓气球鼓室充气治疗难治性梅尼埃病是手术操作方便、安全、经济实用的有效治疗方法。
목적：탐토고막치관관주갑발니룡연합고실충기치료난치성매니애병적료효。방법회고성분석2011년8월—2012년8월재함단시제삼의원주원치료적12례단측난치성매니병환자，재이내경하행고막치관후，고실관주갑발니룡연합고기이경진행고실충기치료，관측환자현훈、은력급이명변화18-24개월。결과현훈완전공제2례，기본공제7례，부분공제2례，무명현변화1례。은력0.5、1、2、3KHz기도평균은역치제고10dBHL2례，제고5 dBHL3례，은력미개선6례，1례은력하강10dBHL。이명소실자4례，명현감경자6례，무명현변화자2례。결론응용고막치관관주갑발니룡연합고실충기치료난치성매니애병，단기가유효적공제현훈，명현개선이명，은력개선불명현。대우상규약물치료무효적MD환자，선택고막치관관주갑발니룡연합고기구고실충기치료난치성매니애병시수술조작방편、안전、경제실용적유효치료방법。
Objective To evaluate the efficacy of intratympanic methylprednisolone perfusion and tympanum inflation in patients with intractable Meniere’s disease(MD). Methods Twelve cases (12 ears) of intractable MD, treated by the authors from August 2011 to August 2012, were studied retrospectively. After the micro-catheter was placed into the tympanum of the affected ear, methylprednisolone was injected and the tympanum inflated with air. The patients were observed for six months for changes in vertigo, hearing loss and tinnitus. Results Vertigo was completely controlled in 2 patients, mostly controlled in 7 patients, partially controlled in 2 patients, and not controlled in 1 patient. The average Tinnitus Handicap Inventory score of was Hearing improved by 10 dB in 2 patients, improved 5 dB in 3 patients, 0 dB in 6 patients and worsened in 1 patient. Tinni?tus disappeared in 4 patients, softened in 6 patients and showed no change in 2 patients. Conclusion Intratympanic methyl?prednisolone perfusion and tympanum inflation through the micro-catheter is a safe and effective method worth trying for in?tractable Meniere’s disease.