CAJ | 학술논문

目的：研究特定内胚层对中耳听骨（耳小柱）发育及其与内耳的整合作用。方法采用鹌鹑-鸡胚移植法，研究R4、R4R5区咽囊内胚层对耳小柱及其与内耳整合的影响。结果咽囊内胚层R4区成功诱导了耳小柱的发育，并随供体位置的轻度偏移诱导耳小柱不同部位的发育；而R4R5区能同时诱导耳小柱内侧段和内耳的发育。结论特定咽囊内胚层能诱导中耳听骨的发育及其与内耳的整合作用。
목적：연구특정내배층대중이은골（이소주）발육급기여내이적정합작용。방법채용암순-계배이식법，연구R4、R4R5구인낭내배층대이소주급기여내이정합적영향。결과인낭내배층R4구성공유도료이소주적발육，병수공체위치적경도편이유도이소주불동부위적발육；이R4R5구능동시유도이소주내측단화내이적발육。결론특정인낭내배층능유도중이은골적발육급기여내이적정합작용。
Objective Investigate the role of pharyngeal pouch endoderm (PPE) to the columella development and its in?tegration with inner ear. Method Observe the effect after PPE in R4 and R4R5 being transplanted isotopically by quail-chick chimera. Results R4 PPE induced the columella’s development and interferance different parts with deviating from R4 slight?ly, while R4R5 affecte development of columella and inner ear simutanously. Conclusions PPE can induce columella devel?opment and its integration with inner ear.