CAJ | 학술논문

目的：评估单侧低中频下降型突发性聋的相关因素对预后的影响。方法由2005~2013年入院的单侧低中频下降型突发性聋109例，均给以改善微循环加激素静点及其他对症治疗。患者按照性别、发病年龄、病程、听力损失程度、高频听力是否损伤、伴有糖尿病，高脂血症等因素分组，分析各因素与疗效（有效，无效）的相关性。先行单因素分析，可能影响疗效的因素再行logistic线性回归分析。结果在此次研究中，单侧低中频下降型突发性聋总有效率为73.4%(80/109)，治愈率71.6%(78/109)。无效率为26.6%(29/109)，患者性别、病程、听力损失程度、高频听力是否损伤、高脂血症，血粘稠度对疗效无明显影响；发病年龄和伴有糖尿病对疗效产生影响。结论年龄大于50岁、空腹血糖≥7.0mmol的单侧低中频下降型突发性聋患者疗效差。
목적：평고단측저중빈하강형돌발성롱적상관인소대예후적영향。방법유2005~2013년입원적단측저중빈하강형돌발성롱109례，균급이개선미순배가격소정점급기타대증치료。환자안조성별、발병년령、병정、은력손실정도、고빈은력시부손상、반유당뇨병，고지혈증등인소분조，분석각인소여료효（유효，무효）적상관성。선행단인소분석，가능영향료효적인소재행logistic선성회귀분석。결과재차차연구중，단측저중빈하강형돌발성롱총유효솔위73.4%(80/109)，치유솔71.6%(78/109)。무효솔위26.6%(29/109)，환자성별、병정、은력손실정도、고빈은력시부손상、고지혈증，혈점주도대료효무명현영향；발병년령화반유당뇨병대료효산생영향。결론년령대우50세、공복혈당≥7.0mmol적단측저중빈하강형돌발성롱환자료효차。
Objective To investigate factors affecting unilateral low-middle frequency sudden hearing loss . Methods This is a retrospective analysis of 109 cases (109ears) of unilateral low-middle frequency sudden hearing loss from 2005 to 2013. Treatments included vasodilators and glucocorticoids. Cases were grouped based on gender, onset age, daration of dis?ease, degree of hearing loss, presence of high frequency hearing damage, comorbid diabetes mellitus, hyperlipidemia and oth?er factor. Correlations between these factors and treatment efficacy were studied using variable analysis followed by logistic linear regression analysis. Results In this study, the total effectiveness rate was 73.4%(80/109). The rates of full recovery and no efficiency were 71.6%(78/109) and 26.6%(29/109), respectively. Patients' gender, disease duration, degree of hear?ing loss, high frequency hearing impairment, hyperlipidemia, and blood viscosity had no obvious effects on treatment out?comes, whereas onset age and co-existing diabetes did. Conclusion Age over 50 years and glucose levels higher than 7.0 mol/l can negatively affect treatment outcomes in unilateral low-middel frequency sudden hearing loss.