CAJ | 학술논문

目的：分析双侧突发性耳聋的临床特点和治疗方法。方法回顾性分析2012年1月至2013年6月确诊并接受治疗的8例双侧突发性耳聋患者的临床资料，包括临床表现，听力学检查，影像学检查，血液学检查，治疗方法及效果评估等，探讨双侧突发性耳聋的临床特征及治疗方法。结果7例双耳同时发病，1例双耳先后发病。白细胞计数异常1例，血液流变学异常5例，风疹病毒、巨细胞病毒、单纯疱疹病毒IgG抗体异常6例（2例未查），凝血功能均无异常，8例患者纤维蛋白原均升高，血糖增高1例，血脂升高1例。心电图和影像学检查结果均正常。采用分型治疗后，8例患者痊愈1耳，显效0耳，有效0耳，总有效率为6.25%。结论双侧突发性耳聋发病原因多样化，病情复杂，预后较单侧突发性耳聋差，须针对不同类型听力曲线采取分型治疗。
목적：분석쌍측돌발성이롱적림상특점화치료방법。방법회고성분석2012년1월지2013년6월학진병접수치료적8례쌍측돌발성이롱환자적림상자료，포괄림상표현，은역학검사，영상학검사，혈액학검사，치료방법급효과평고등，탐토쌍측돌발성이롱적림상특정급치료방법。결과7례쌍이동시발병，1례쌍이선후발병。백세포계수이상1례，혈액류변학이상5례，풍진병독、거세포병독、단순포진병독IgG항체이상6례（2례미사），응혈공능균무이상，8례환자섬유단백원균승고，혈당증고1례，혈지승고1례。심전도화영상학검사결과균정상。채용분형치료후，8례환자전유1이，현효0이，유효0이，총유효솔위6.25%。결론쌍측돌발성이롱발병원인다양화，병정복잡，예후교단측돌발성이롱차，수침대불동류형은력곡선채취분형치료。
Objective To report characteristics and treatment outcomes in patients with bilateral sudden sensorineural hearing loss (BSSHL). Methods From Jan 2012 to June 2013, 318 patients with sudden sensorineural hearing loss were treat?ed by the authors. Of these, 8 (2.5%) had BSSHL. We reviewed the charts of these 8 patients, focusing on clinical manifesta?tions, audiologic characteristics, radiography, laboratory results and treatment outcomes. Results Seven of the 8 patients re?ported simultaneous BSSHL, and the other one had sequential BSSHL. Electrocardiogram, CT and MRI were normal in all pa?tients. Abnormal white blood cell count was seen in one case, increased blood viscosities in 5 cases, increased virus antibod?ies in 6 cases, abnormal glucose in 1 case, abnormal lipid metabolism profile in 1 case, and increased fibrinogen levels in all 8 cases. After combined multiple therapies tailored to each patient based on subtypes of audiogram, complete hearing recov?ery was achieved in 1 ear (6.25%), while the rest showed no responses. Conclusion BSSHL is a complex condition with vari?able etiological factors and poor prognosis. It may need to be treated based upon subtypes of audiogram.