CAJ | 학술논문

目的：调查分析宁波地区某三甲综合医院住院患者人血白蛋白的临床应用现状及特点，评价用药合理性。方法回顾性调查该院2012年1月至12月所有使用人血白蛋白的住院患者病历，统计人血白蛋白使用的临床科室分布、用量、用药前白蛋白水平、用药原因等。结果2012年共有1580例患者使用过人血白蛋白，总用量为116379．7 g，平均每人消耗73．66 g，涉及科室为27个，92．59％的患者用药前血清白蛋白的浓度低于30 g/L，用药原因以低蛋白血症占多数（48．86％）。结论该院人血白蛋白的使用存在一定的不合理性，应建立人血白蛋白合理用药评估体系，对临床不合理应用进行干预以提高用药合理性，并呼吁尽快制定基于循证医学的指南。
목적：조사분석저파지구모삼갑종합의원주원환자인혈백단백적림상응용현상급특점，평개용약합이성。방법회고성조사해원2012년1월지12월소유사용인혈백단백적주원환자병력，통계인혈백단백사용적림상과실분포、용량、용약전백단백수평、용약원인등。결과2012년공유1580례환자사용과인혈백단백，총용량위116379．7 g，평균매인소모73．66 g，섭급과실위27개，92．59％적환자용약전혈청백단백적농도저우30 g/L，용약원인이저단백혈증점다수（48．86％）。결론해원인혈백단백적사용존재일정적불합이성，응건립인혈백단백합리용약평고체계，대림상불합리응용진행간예이제고용약합이성，병호우진쾌제정기우순증의학적지남。
Objective To investigate the current application and characteristics of human serum albumin in hospitalized patients of a 3A grade general hospital in Ningbo, and evaluate the rationality of medication. Methods The medical records of all hospitalized patients given human serum albumin between January and December 2012 were retrospectively investigated. The distribution of clinical department, dosage, human serum albumin level before medication and the reasons of using human serum albumin were statistically analyzed. Results The total dosage in 1580 cases given human serum albumin in 2012 was 116 379.7 g with a mean consumption of 73.66 g for each pa-tient, involving 27 departments. The concentration of serum albumin before medication in 92.59% of the patients was under 30 g/L. And the leading cause of albumin use was hypoalbuminemia, found in 48.86%of the patients. Conclu-sion Certain irrational use of human serum albumin may be present in this hospital. Evaluation system of rational hu-man serum albumin use should be established, and irrational practice should be intervened to improve the rationality of medication. Development of evidence-based guidelines on proper albumin use as soon as possible should be expected.