CAJ | 학술논문

维生素D对钙磷代谢具有调节作用，并对骨骼健康会产生影响。但是维生素D及其代谢物广泛的生理作用远不只是对骨骼的生物学效应，许多生理过程都直接或间接受维生素D调节。近年来，维生素D在骨质代谢和钙调节之外的作用越来越受到重视。慢性阻塞性肺疾病（COPD）是一种进行性呼吸功能减退的呼吸道疾病，在老年人群中发病率很高。有研究表明，COPD的严重程度与维生素D缺乏相关。本文的主要目的是提高医务工作者对维生素D与COPD相关性的认识，并评估补充维生素D对减轻COPD患者病情的潜在作用。
유생소D대개린대사구유조절작용，병대골격건강회산생영향。단시유생소D급기대사물엄범적생리작용원불지시대골격적생물학효응，허다생리과정도직접혹간접수유생소D조절。근년래，유생소D재골질대사화개조절지외적작용월래월수도중시。만성조새성폐질병（COPD）시일충진행성호흡공능감퇴적호흡도질병，재노년인군중발병솔흔고。유연구표명，COPD적엄중정도여유생소D결핍상관。본문적주요목적시제고의무공작자대유생소D여COPD상관성적인식，병평고보충유생소D대감경COPD환자병정적잠재작용。
Vitamin D plays a vital role in the regulation of calcium and phosphate metabolism, and exerts essential effects on bone health. However, the wide-spread physiological roles of vitamin D and its metabolites are far beyond these well described effects in skeletal biology. Many physiological processes are directly or indirectly regulated by vitamin D. In recent years, more and more emphasis has been given to the roles of vitamin D in the other aspects besides bone metabolism and calcium homeostasis. Chronic obstructive pulmonary disease (COPD) is a progressive functional disorder in the respiratory system with high prevalence in the older population. Evidence shows there is a correlation between the severity of COPD and vitamin D deficiency. This article aims to update the knowledge about the association of vitamin D with COPD, as well as to assess the potential role of vitamin D supplements in treatment of the disease.