CAJ | 학술논문

目的：探讨静脉留置针在清醒大鼠尾静脉的留置时间。方法将100只Wistar大鼠随机分为两组，即实验组和对照组，采取相同的方法分别进行尾静脉留置针穿刺和置管，对照组采取传统的固定方法，即用3M透明敷贴固定；实验组在此基础上，再用厚约0．1 mm的铝合金皮套管环形包裹在留置针外侧，分别记录留置时间。结果实验组大鼠尾静脉留置针的留置时间为（166．86±9．03）h，对照组的留置时间为（20．24±5．04） h，两组留置时间相比较，差异明显有统计学意义（ P<0．01）。结论改良的固定方法安全可靠，能够延长静脉留置针的留置时间，为静脉留置针并发症的实验研究提供了一定的基础。
목적：탐토정맥류치침재청성대서미정맥적류치시간。방법장100지Wistar대서수궤분위량조，즉실험조화대조조，채취상동적방법분별진행미정맥류치침천자화치관，대조조채취전통적고정방법，즉용3M투명부첩고정；실험조재차기출상，재용후약0．1 mm적려합금피투관배형포과재류치침외측，분별기록류치시간。결과실험조대서미정맥류치침적류치시간위（166．86±9．03）h，대조조적류치시간위（20．24±5．04） h，량조류치시간상비교，차이명현유통계학의의（ P<0．01）。결론개량적고정방법안전가고，능구연장정맥류치침적류치시간，위정맥류치침병발증적실험연구제공료일정적기출。
Objective To improve the fixation method of indwelling needle inserted in the tail vein in rats to keep the inserted needle for a longer indwelling time .Methods One hundred healthy Wistar rats ( age 5~6 months, male:female=1:1) were randomly divided into two groups: the experimental group and the control group .Rats in both groups received the same tail vein indwelling needle puncture and cannulation .The control group got the traditional fixation , namely fixed by sticking with 3M transparent dressing paste .The experimental group received in addition to the traditional fixation, a 0.1 mm-thick aluminum tube placed outside the needle fixation site .The indwelling time in the rats were recorded and analyzed .Results The indwelling time was (166.86 ±9.03) h and (20.24 ±5.04) h in the experimental and control groups, respectively (t =68.546, P<0.01).Conclusions Our improved method is safe and reliable.It can prolong the indwelling time of the punctured intravenous indwelling needle , and provides a useful rat model in studies on the complications of intravenous indwelling needle kept for a longer time .