CAJ | 학술논문

目的：探讨我院药品不良反应（ADR）一般规律与发生因素和特征，从而为临床合理用药和安全用药提供依据。方法收集2012～2013年127例药物不良反应报告进行分析，根据药品的给药途径、药品类型、ADR程度、ADR所涉及器官和系统、临床表现等做分析。结果本次研究中共涉及127份药物，其中抗菌药物居首位，中成药紧随其后；因静脉滴注而引发的ADR121例，占95.3%；DAR可发生于人体内的每个系统和器官，可表现为变态反应，皮肤损害最为严重，其次为神经系统受损。结论应该针对DAR情况加强监测力度，并将ADR的相关知识进行宣传普及，指导临床进行合理用药，尽量将DAR发生率降至最低。
목적：탐토아원약품불량반응（ADR）일반규률여발생인소화특정，종이위림상합리용약화안전용약제공의거。방법수집2012～2013년127례약물불량반응보고진행분석，근거약품적급약도경、약품류형、ADR정도、ADR소섭급기관화계통、림상표현등주분석。결과본차연구중공섭급127빈약물，기중항균약물거수위，중성약긴수기후；인정맥적주이인발적ADR121례，점95.3%；DAR가발생우인체내적매개계통화기관，가표현위변태반응，피부손해최위엄중，기차위신경계통수손。결론응해침대DAR정황가강감측력도，병장ADR적상관지식진행선전보급，지도림상진행합리용약，진량장DAR발생솔강지최저。
Objective Investigate adverse drug reactions (ADR) and the occurrence of the general rules of the factors and characteristics, Thus provide the basis for clinical use of drugs and medication safety. Methods 2012-2013 collected 127 cases of adverse drug reaction reports for analysis, According to the route of administration of drugs, drug type, ADR extent, ADR and the organ systems involved in doing analysis and other clinical manifestations.Results The study involved 127 CPC drugs, Wherein the antimicrobial drugs in the first place, Followed by medicine; Caused due to intravenous ADR121 cases,Accounting for 95.3%; DAR can occur in the human body every system and organ, Can be expressed as allergy, The most serious skin damage, Followed by nervous system damage.Conclusion Monitoring efforts should strengthen the case for the DAR, ADR-related knowledge and conduct outreach, Clinical rational drug use, Try to minimize the incidence of DAR.