中华实验和临床感染病杂志(电子版)
中華實驗和臨床感染病雜誌(電子版)
중화실험화림상감염병잡지(전자판)
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2014年
6期
774-776
,共3页
嗜麦芽窄食单胞菌%菌株来源%药敏试验%耐药性
嗜麥芽窄食單胞菌%菌株來源%藥敏試驗%耐藥性
기맥아착식단포균%균주래원%약민시험%내약성
Stenotrophomonas maltophilia%Source of strain%Susceptibility test%Drug resistance
目的:分析泰安市中心医院重症医学科嗜麦芽窄食单胞菌的分布及耐药性,为临床合理使用抗菌药物及控制医院感染提供依据。方法采用Microscan WalkAway 96 Plus全自动微生物鉴定及药敏系统进行菌株鉴定和药敏试验,对2012年10月至2013年12月本院重症医学科分离的嗜麦芽窄食单胞菌分布情况及耐药性进行回顾性分析。结果临床标本共分离出嗜麦芽窄食单胞菌65株,其中50岁以上患者占60.0%(39/65);主要分离自痰液,占90.8%(59/65),其他依次为分泌物4.6%(3/65)、血液1.5%(1/65)、胸水1.5%(1/65)和尿液1.5%(1/65);对替卡西林/克拉维酸、头孢他啶、左氧氟沙星和磺胺甲噁唑/甲氧苄啶耐药率依次为61.5%(40/65)、87.7%(57/65)、7.7%(5/65)和0(0/65),敏感率依次为13.8%(9/65)、7.7%(5/65)、90.8%(59/65)和100%(65/65)。结论嗜麦芽窄食单胞菌主要引起呼吸道感染,对替卡西林/克拉维酸及头孢他啶耐药严重,对磺胺甲噁唑/甲氧苄啶最敏感,临床上应根据本地区的流行病学特点合理选用抗菌药物。
目的:分析泰安市中心醫院重癥醫學科嗜麥芽窄食單胞菌的分佈及耐藥性,為臨床閤理使用抗菌藥物及控製醫院感染提供依據。方法採用Microscan WalkAway 96 Plus全自動微生物鑒定及藥敏繫統進行菌株鑒定和藥敏試驗,對2012年10月至2013年12月本院重癥醫學科分離的嗜麥芽窄食單胞菌分佈情況及耐藥性進行迴顧性分析。結果臨床標本共分離齣嗜麥芽窄食單胞菌65株,其中50歲以上患者佔60.0%(39/65);主要分離自痰液,佔90.8%(59/65),其他依次為分泌物4.6%(3/65)、血液1.5%(1/65)、胸水1.5%(1/65)和尿液1.5%(1/65);對替卡西林/剋拉維痠、頭孢他啶、左氧氟沙星和磺胺甲噁唑/甲氧芐啶耐藥率依次為61.5%(40/65)、87.7%(57/65)、7.7%(5/65)和0(0/65),敏感率依次為13.8%(9/65)、7.7%(5/65)、90.8%(59/65)和100%(65/65)。結論嗜麥芽窄食單胞菌主要引起呼吸道感染,對替卡西林/剋拉維痠及頭孢他啶耐藥嚴重,對磺胺甲噁唑/甲氧芐啶最敏感,臨床上應根據本地區的流行病學特點閤理選用抗菌藥物。
목적:분석태안시중심의원중증의학과기맥아착식단포균적분포급내약성,위림상합리사용항균약물급공제의원감염제공의거。방법채용Microscan WalkAway 96 Plus전자동미생물감정급약민계통진행균주감정화약민시험,대2012년10월지2013년12월본원중증의학과분리적기맥아착식단포균분포정황급내약성진행회고성분석。결과림상표본공분리출기맥아착식단포균65주,기중50세이상환자점60.0%(39/65);주요분리자담액,점90.8%(59/65),기타의차위분비물4.6%(3/65)、혈액1.5%(1/65)、흉수1.5%(1/65)화뇨액1.5%(1/65);대체잡서림/극랍유산、두포타정、좌양불사성화광알갑오서/갑양변정내약솔의차위61.5%(40/65)、87.7%(57/65)、7.7%(5/65)화0(0/65),민감솔의차위13.8%(9/65)、7.7%(5/65)、90.8%(59/65)화100%(65/65)。결론기맥아착식단포균주요인기호흡도감염,대체잡서림/극랍유산급두포타정내약엄중,대광알갑오서/갑양변정최민감,림상상응근거본지구적류행병학특점합리선용항균약물。
Objective To investigate the distribution and drug resistance of Stenotrophomonas maltophilia in Intensive Care Unit (ICU), and provide the basis for the clinical treatment and control nosocomial infection. Methods The bacterial identiifcation and susceptibility test were done by Microscan WalkAway 96 Plus automated microbial identification system. The distribution and drug resistance of Stenotrophomonas maltophilia isolated from ICU from October 2012 to December 2013 in our hospital were analyzed, retrospectively. Results Total of 65 strains of Stenotrophomonas maltophilia were isolated, among which, patients over 50 years accounted for 60.0% (39/65); mainly from sputum, accounting for 90.8%(59/65), followed by secretion of 4.6%(3/65), blood of 1.5%(1/65), pleural effusion of 1.5%(1/65) and urine of 1.5% (1/65). The resistance rates of Stenotrophomonas maltophilia to ticarcillin/clavulanic, ceftazidime, levofloxacin and sulfamethoxazole/trimethoprim were 61.5% (40/65), 87.7% (57/65), 7.7%(5/65) and 0 (0/65), respectively; and the sensitive rates were 13.8% (9/65), 7.7% (5/65), 90.8% (59/65) and 100% (65/65), respectively. Conclusions Stenotrophomonas maltophilia mainly caused respiratory infection. Drug resistance to ticarcillin/clavulanic and ceftazidime were severe, and sulfamethoxazole/trimethoprim was most sensitive. The proper antibiotics should be chosen according to the epidemiological characteristics of the local.